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1LPZ

CRYSTAL STRUCTURE OF FXA IN COMPLEX WITH 41.

Summary for 1LPZ
Entry DOI10.2210/pdb1lpz/pdb
Related1LPG 1LPK 1LQD 1LQE
DescriptorBlood coagulation factor Xa, CALCIUM ION, 1-(3-carbamimidoylbenzyl)-N-(3,5-dichlorobenzyl)-4-methyl-1H-indole-2-carboxamide, ... (5 entities in total)
Functional Keywordsprotein inhibitor complex, blood coagulation factor, serine proteinase, hydrolase
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted: P00742 P00742
Total number of polymer chains2
Total formula weight44266.84
Authors
Schreuder, H.A.,Brachvogel, V.,Liesum, A. (deposition date: 2002-05-08, release date: 2003-05-08, Last modification date: 2011-07-13)
Primary citationMatter, H.,Defossa, E.,Heinelt, U.,Blohm, P.M.,Schneider, D.,Mueller, A.,Herok, S.,Schreuder, H.A.,Liesum, A.,Brachvogel, V.,Loenze, P.,Walser, A.,Al-Obeidi, F.,Wildgoose, P.
Design and Quantitative Structure-Activity relationship of 3-amidinobenzyl-1H-indole-2-carboxamides as potent, nonchiral, and selective inhibitors of blood coagulation factor Xa
J.Biol.Chem., 45:2749-2769, 2002
Cited by
PubMed: 12061878
DOI: 10.1021/jm0111346
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

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