1IQE

Human coagulation factor Xa in complex with M55590

Summary for 1IQE

• Entry DOI: 10.2210/pdb1iqe/pdb
• Related: 1IOE 1IQF 1IQG 1IQH 1IQI 1IQJ 1IQK 1IQL 1IQM 1IQN
• Descriptor: coagulation Factor Xa, CALCIUM ION, 4-[(2R)-3-[[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]AMINO]-1-OXO-2-[[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]AMINO]PROPYL]-THIOMORPHOLINE-1,1-DIOXIDE, ... (4 entities in total)
• Functional Keywords: hydrolase, serine protease, blood coagulation factor, complex
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P00742 P00742
• Total number of polymer chains: 2
• Total formula weight: 37798.27

Authors

Shiromizu, I.,Matsusue, T. (deposition date: 2001-07-23, release date: 2003-09-23, Last modification date: 2023-12-27)

• Primary citation: Matsusue, T.,Shiromizu, I.,Okamoto, A.,Nakayama, K.,Nishida, H.,Mukaihira, T.,Miyazaki, Y.,Saitou, F.,Morishita, H.,Ohnishi, S.,Mochizuki, H.; Factor Xa Specific Inhibitor that Induces the Novel Binding Model in Complex with Human Fxa; To be Published,

Experimental method

X-RAY DIFFRACTION (2.9 Å)