1IQE
Human coagulation factor Xa in complex with M55590
Summary for 1IQE
Entry DOI | 10.2210/pdb1iqe/pdb |
Related | 1IOE 1IQF 1IQG 1IQH 1IQI 1IQJ 1IQK 1IQL 1IQM 1IQN |
Descriptor | coagulation Factor Xa, CALCIUM ION, 4-[(2R)-3-[[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]AMINO]-1-OXO-2-[[[1-(4-PYRIDINYL)-4-PIPERIDINYL]METHYL]AMINO]PROPYL]-THIOMORPHOLINE-1,1-DIOXIDE, ... (4 entities in total) |
Functional Keywords | hydrolase, serine protease, blood coagulation factor, complex |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P00742 P00742 |
Total number of polymer chains | 2 |
Total formula weight | 37798.27 |
Authors | Shiromizu, I.,Matsusue, T. (deposition date: 2001-07-23, release date: 2003-09-23, Last modification date: 2023-12-27) |
Primary citation | Matsusue, T.,Shiromizu, I.,Okamoto, A.,Nakayama, K.,Nishida, H.,Mukaihira, T.,Miyazaki, Y.,Saitou, F.,Morishita, H.,Ohnishi, S.,Mochizuki, H. Factor Xa Specific Inhibitor that Induces the Novel Binding Model in Complex with Human Fxa To be Published, |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
Download full validation report