1FAX
COAGULATION FACTOR XA INHIBITOR COMPLEX
Summary for 1FAX
Entry DOI | 10.2210/pdb1fax/pdb |
Descriptor | FACTOR XA, CALCIUM ION, (2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-[4-({(3R)-1-[(1Z)-ethanimidoyl]pyrrolidin-3-yl}oxy)phenyl]propanoic acid, ... (4 entities in total) |
Functional Keywords | glycoprotein, hydrolase, serine protease, plasma, blood coagulation factor, gamma-carboxyglutamic acid, calcium-binding, coagulation factor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P00742 P00742 |
Total number of polymer chains | 2 |
Total formula weight | 39410.80 |
Authors | Brandstetter, H.,Engh, R.A. (deposition date: 1996-08-23, release date: 1997-10-29, Last modification date: 2011-07-13) |
Primary citation | Brandstetter, H.,Kuhne, A.,Bode, W.,Huber, R.,von der Saal, W.,Wirthensohn, K.,Engh, R.A. X-ray structure of active site-inhibited clotting factor Xa. Implications for drug design and substrate recognition. J.Biol.Chem., 271:29988-29992, 1996 Cited by PubMed: 8939944DOI: 10.1074/jbc.271.47.29988 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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