1XKA

FACTOR XA COMPLEXED WITH A SYNTHETIC INHIBITOR FX-2212A,(2S)-(3'-AMIDINO-3-BIPHENYLYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID

Summary for 1XKA

Entry DOI	10.2210/pdb1xka/pdb
Descriptor	BLOOD COAGULATION FACTOR XA, CALCIUM ION, (2S)-(3'-AMIDINO-3-BIPHENYL)-5-(4-PYRIDYLAMINO)PENTANOIC ACID, ... (5 entities in total)
Functional Keywords	blood coagulation factor, serine proteinase, epidermal growth factor like domain
Biological source	Homo sapiens (human) More
Cellular location	Secreted: P00742 P00742
Total number of polymer chains	2
Total formula weight	37419.38
Authors	Kamata, K.,Kim, S.H. (deposition date: 1998-03-19, release date: 1999-03-23, Last modification date: 2023-08-09)
Primary citation	Kamata, K.,Kawamoto, H.,Honma, T.,Iwama, T.,Kim, S.H. Structural basis for chemical inhibition of human blood coagulation factor Xa. Proc.Natl.Acad.Sci.USA, 95:6630-6635, 1998 Cited by PubMed: 9618463 DOI: 10.1073/pnas.95.12.6630 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation