1MDY
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CRYSTAL STRUCTURE OF MYOD BHLH DOMAIN BOUND TO DNA: PERSPECTIVES ON DNA RECOGNITION AND IMPLICATIONS FOR TRANSCRIPTIONAL ACTIVATION
Descriptor:DNA (5'-D(*TP*CP*AP*AP*CP*AP*GP*CP*TP*GP*TP*TP*GP*A)-3'), PROTEIN (MYOD BHLH DOMAIN)
Authors:Ma, P.C.M., Rould, M.A., Weintraub, H., Pabo, C.O.
Deposit date:1994-06-09
Release date:1994-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of MyoD bHLH domain-DNA complex: perspectives on DNA recognition and implications for transcriptional activation.
Cell(Cambridge,Mass.), 77, 1994
1A0A
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PHOSPHATE SYSTEM POSITIVE REGULATORY PROTEIN PHO4/DNA COMPLEX
Descriptor:DNA (5'-D(*CP*TP*CP*AP*CP*AP*CP*GP*TP*GP*GP*GP*AP*CP*TP*AP*G )-3'), DNA (5'-D(*CP*TP*AP*GP*TP*CP*CP*CP*AP*CP*GP*TP*GP*TP*GP*AP*G )-3'), PROTEIN (PHOSPHATE SYSTEM POSITIVE REGULATORY PROTEIN PHO4)
Authors:Shimizu, T., Toumoto, A., Ihara, K., Shimizu, M., Kyogoku, Y., Ogawa, N., Oshima, Y., Hakoshima, T.
Deposit date:1997-11-27
Release date:1998-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of PHO4 bHLH domain-DNA complex: flanking base recognition.
EMBO J., 16, 1997
2QL2
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CRYSTAL STRUCTURE OF THE BASIC-HELIX-LOOP-HELIX DOMAINS OF THE HETERODIMER E47/NEUROD1 BOUND TO DNA
Descriptor:Transcription factor E2-alpha, Neurogenic differentiation factor 1, DNA (5'-D(*DTP*DAP*DGP*DGP*DCP*DCP*DAP*DTP*DCP*DTP*DGP*DGP*DTP*DCP*DCP*DT)-3'), ...
Authors:Rose, R.B., Longo, A., Guanga, G.P.
Deposit date:2007-07-12
Release date:2008-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of E47-NeuroD1/beta2 bHLH domain-DNA complex: heterodimer selectivity and DNA recognition.
Biochemistry, 47, 2008
5SY5
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CRYSTAL STRUCTURE OF THE HETERODIMERIC NPAS1-ARNT COMPLEX
Descriptor:Aryl hydrocarbon receptor nuclear translocator, Neuronal PAS domain-containing protein 1
Authors:Wu, D., Su, X., Potluri, N., Kim, Y., Rastinejad, F.
Deposit date:2016-08-10
Release date:2016-11-09
Method:X-RAY DIFFRACTION (3.201 Å)
Cite:NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors.
Elife, 5, 2016
5SY7
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CRYSTAL STRUCTURE OF THE HETERODIMERIC NPAS3-ARNT COMPLEX WITH HRE DNA
Descriptor:Aryl hydrocarbon receptor nuclear translocator, Neuronal PAS domain-containing protein 3, DNA (5'-D(*GP*GP*CP*TP*GP*CP*GP*TP*AP*CP*GP*TP*GP*CP*GP*GP*GP*TP*CP*GP*T)-3'), ...
Authors:Wu, D., Su, X., Potluri, N., Kim, Y., Rastinejad, F.
Deposit date:2016-08-10
Release date:2016-11-09
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors.
Elife, 5, 2016
6QTV
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CRYSTAL STRUCTURE OF AN ARABIDOPSIS WD40 DOMAIN IN COMPLEX WITH AN ATYPICAL BHLH TRANSCRIPTION FACTOR
Descriptor:E3 ubiquitin-protein ligase COP1, Transcription factor HFR1, MALONATE ION, ...
Authors:Hothorn, M., Lau, K.
Deposit date:2019-02-25
Release date:2019-07-10
Last modified:2019-10-02
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Plant photoreceptors and their signaling components compete for COP1 binding via VP peptide motifs.
Embo J., 38, 2019
6OD3
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HUMAN TCF4 C-TERMINAL BHLH DOMAIN IN COMPLEX WITH 13-BP OLIGONUCLEOTIDE CONTAINING E-BOX SEQUENCE
Descriptor:Transcription factor 4, DNA (5'-D(*CP*AP*TP*AP*CP*AP*CP*GP*TP*GP*TP*AP*T)-3'), 1,2-ETHANEDIOL, ...
Authors:Horton, J.R., Cheng, X., Yang, J.
Deposit date:2019-03-25
Release date:2019-05-29
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.494 Å)
Cite:Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine.
Nucleic Acids Res., 47, 2019
6OD4
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HUMAN TCF4 C-TERMINAL BHLH DOMAIN IN COMPLEX WITH 11-BP OLIGONUCLEOTIDE CONTAINING E-BOX SEQUENCE
Descriptor:Transcription factor 4, DNA (5'-D(*TP*AP*CP*AP*CP*GP*TP*GP*TP*A)-3'), 1,2-ETHANEDIOL
Authors:Horton, J.R., Cheng, X., Yang, J.
Deposit date:2019-03-25
Release date:2019-05-29
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.699 Å)
Cite:Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine.
Nucleic Acids Res., 47, 2019
6OD5
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HUMAN TCF4 C-TERMINAL BHLH DOMAIN IN COMPLEX WITH 12-BP OLIGONUCLEOTIDE CONTAINING E-BOX SEQUENCE WITH 5-CARBOXYLCYTOSINES
Descriptor:Transcription factor 4, DNA (5'-D(*AP*(1CC)P*GP*CP*AP*CP*GP*TP*GP*(1CC)P*G)-3'), 1,2-ETHANEDIOL, ...
Authors:Horton, J.R., Cheng, X., Yang, J.
Deposit date:2019-03-25
Release date:2019-05-29
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine.
Nucleic Acids Res., 47, 2019
5EYO
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THE CRYSTAL STRUCTURE OF THE MAX BHLH DOMAIN IN COMPLEX WITH 5-CARBOXYL CYTOSINE DNA
Descriptor:Protein max, DNA (5'-D(*AP*GP*TP*AP*GP*CP*AP*(1CC)P*GP*TP*GP*CP*TP*AP*CP*T)-3')
Authors:Wang, D., Hashimoto, H., Zhang, X., Cheng, X.
Deposit date:2015-11-25
Release date:2016-12-14
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma.
Nucleic Acids Res., 45, 2017
4H10
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INTERMOLECULAR RECOGNITION REVEALED BY THE COMPLEX STRUCTURE OF HUMAN CLOCK-BMAL1 BASIC HELIX-LOOP-HELIX DOMAINS WITH E-BOX DNA
Descriptor:Aryl hydrocarbon receptor nuclear translocator-like protein 1, Circadian locomoter output cycles protein kaput, E-box DNA sense strand, ...
Authors:Wang, Z., Su, X.-D.
Deposit date:2012-09-10
Release date:2012-12-26
Last modified:2013-02-20
Method:X-RAY DIFFRACTION (2.402 Å)
Cite:Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic helix-loop-helix domains with E-box DNA.
Cell Res., 23, 2013
4RQW
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CRYSTAL STRUCTURE OF MYC3 N-TERMINAL JAZ-BINDING DOMAIN [44-238] FROM ARABIDOPSIS
Descriptor:Transcription factor MYC3, CALCIUM ION
Authors:Ke, J., Zhang, F., Zhou, X.E., Brunzelle, J., Zhou, M., Xu, H.E., Melcher, K., He, S.Y.
Deposit date:2014-11-05
Release date:2015-08-12
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
4RRU
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MYC3 N-TERMINAL JAZ-BINDING DOMAIN[5-242] FROM ARABIDOPSIS
Descriptor:Transcription factor MYC3, CALCIUM ION
Authors:Ke, J., Zhang, F., Zhou, X.E., Brunzelle, J.S., Zhou, M., Xu, H.E., Melcher, K., He, S.Y.
Deposit date:2014-11-06
Release date:2015-08-12
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
4RS9
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STRUCTURE OF MYC3 N-TERMINAL JAZ-BINDING DOMAIN [44-238] IN COMPLEX WITH JAS MOTIF OF JAZ9
Descriptor:Transcription factor MYC3, Protein TIFY 7
Authors:Ke, J., Zhang, F., Zhou, X.E., Brunzelle, J.S., Zhou, M., Xu, H.E., Melcher, K., He, S.Y.
Deposit date:2014-11-07
Release date:2015-08-12
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
4YWC
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CRYSTAL STRUCTURE OF MYC3(5-242) FRAGMENT IN COMPLEX WITH JAZ9(218-239) PEPTIDE
Descriptor:Transcription factor MYC3, Protein TIFY 7
Authors:Ke, J., Zhang, F., Brunzelle, J.S., Xu, H.E., Melcher, K., He, S.Y.
Deposit date:2015-03-20
Release date:2015-08-05
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
4YZ6
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CRYSTAL STRUCTURE OF MYC3[44-238] FROM ARABIDOPSIS IN COMPLEX WITH JAZ1 PEPTIDE [200-221]
Descriptor:Transcription factor MYC3, Protein TIFY 10A
Authors:Ke, J., Zhang, F., Brunzelle, J., Xu, H.E., Melcher, K., HE, S.Y.
Deposit date:2015-03-24
Release date:2015-08-05
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling.
Nature, 525, 2015
5T0F
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CRYSTAL STRUCTURE OF THE MYC3 N-TERMINAL DOMAIN [44-242] IN COMPLEX WITH JAZ10 CMID DOMAIN [16-58] FROM ARABIDOPSIS
Descriptor:Transcription factor MYC3, Protein TIFY 9
Authors:Ke, J., Zhang, F., Brunzelle, J.S., He, S.Y., Xu, H.E., Melcher, K.
Deposit date:2016-08-16
Release date:2017-01-25
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural insights into alternative splicing-mediated desensitization of jasmonate signaling.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5T0Q
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CRYSTAL STRUCTURE OF THE MYC3 N-TERMINAL DOMAIN [44-242] IN COMPLEX WITH JAZ10 JAS DOMAIN [166-192] FROM ARABIDOPSIS
Descriptor:Transcription factor MYC3, Protein TIFY 9
Authors:Ke, J., Zhang, F., Brunzelle, J.S., He, S.Y., Xu, H.E., Melcher, K.
Deposit date:2016-08-16
Release date:2017-01-25
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural insights into alternative splicing-mediated desensitization of jasmonate signaling.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2YPA
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STRUCTURE OF THE SCL:E47:LMO2:LDB1 COMPLEX BOUND TO DNA
Descriptor:T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1, TRANSCRIPTION FACTOR E2-ALPHA, RHOMBOTIN-2, ...
Authors:El Omari, K., Hoosdally, S.J., Tuladhar, K., Karia, D., Ponsele, E., Platonova, O., Vyas, P., Patient, R., Porcher, C., Mancini, E.J.
Deposit date:2012-10-30
Release date:2013-07-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets.
Cell Rep., 4, 2013
2YPB
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STRUCTURE OF THE SCL:E47 COMPLEX BOUND TO DNA
Descriptor:T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1, TRANSCRIPTION FACTOR E2-ALPHA, EBOX FORWARD, ...
Authors:El Omari, K., Hoosdally, S.J., Tuladhar, K., Karia, D., Ponsele, E., Platonova, O., Vyas, P., Patient, R., Porcher, C., Mancini, E.J.
Deposit date:2012-10-30
Release date:2013-07-31
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets.
Cell Rep., 4, 2013
3U5V
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CRYSTAL STRUCTURE OF MAX-E47
Descriptor:Protein max, Transcription factor E2-alpha chimera, NITRATE ION
Authors:Guarne, A., Ahmadpour, F., Gloyd, M.
Deposit date:2011-10-11
Release date:2012-03-21
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the minimalist max-e47 protein chimera.
Plos One, 7, 2012
4F3L
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CRYSTAL STRUCTURE OF THE HETERODIMERIC CLOCK:BMAL1 TRANSCRIPTIONAL ACTIVATOR COMPLEX
Descriptor:BMAL1b, Circadian locomoter output cycles protein kaput
Authors:Huang, N., Chelliah, Y., Shan, Y., Taylor, C., Yoo, S., Partch, C., Green, C.B., Zhang, H., Takahashi, J.
Deposit date:2012-05-09
Release date:2012-06-06
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.268 Å)
Cite:Crystal structure of the heterodimeric CLOCK:BMAL1 transcriptional activator complex.
Science, 337, 2012
5GNJ
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STRUCTURE OF A TRANSCRIPTION FACTOR AND DNA COMPLEX
Descriptor:Transcription factor MYC2, DNA (5'-D(*AP*GP*GP*AP*AP*CP*AP*CP*GP*TP*GP*AP*CP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*GP*TP*CP*AP*CP*GP*TP*GP*TP*TP*CP*C)-3')
Authors:Lian, T., Xu, Y., Su, X.
Deposit date:2016-07-21
Release date:2017-05-10
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of Tetrameric Arabidopsis MYC2 Reveals the Mechanism of Enhanced Interaction with DNA.
Cell Rep, 19, 2017
1AN4
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STRUCTURE AND FUNCTION OF THE B/HLH/Z DOMAIN OF USF
Descriptor:DNA (5'-D(*CP*AP*CP*CP*CP*GP*GP*TP*CP*AP*CP*GP*TP*GP*GP*CP*C P*TP*AP*CP*A)-3'), DNA (5'-D(*GP*TP*GP*TP*AP*GP*GP*CP*CP*AP*CP*GP*TP*GP*AP*CP*C P*GP*GP*GP*T)-3'), PROTEIN (UPSTREAM STIMULATORY FACTOR)
Authors:Ferre-D'Amare, A.R., Pognonec, P., Roeder, R.G., Burley, S.K.
Deposit date:1997-03-15
Release date:1997-09-17
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure and function of the b/HLH/Z domain of USF.
EMBO J., 13, 1994
1J2O
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STRUCTURE OF FLIN2, A COMPLEX CONTAINING THE N-TERMINAL LIM DOMAIN OF LMO2 AND LDB1-LID
Descriptor:Fusion of Rhombotin-2 and LIM domain-binding protein 1, ZINC ION
Authors:Deane, J.E., Mackay, J.P., Kwan, A.H., Sum, E.Y., Visvader, J.E., Matthews, J.M.
Deposit date:2003-01-08
Release date:2003-05-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural basis for the recognition of ldb1 by the N-terminal LIM domains of LMO2 and LMO4
EMBO J., 22, 2003
171313
PDB entries from 2020-11-18