6OD4

Human TCF4 C-terminal bHLH domain in Complex with 11-bp Oligonucleotide Containing E-box Sequence

Summary for 6OD4

• Entry DOI: 10.2210/pdb6od4/pdb
• Descriptor: Transcription factor 4, DNA (5'-D(*TP*AP*CP*AP*CP*GP*TP*GP*TP*A)-3'), 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: protein-dna complex, transcription factor, bhth, e-box, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 36365.43

Authors

Horton, J.R.,Cheng, X.,Yang, J. (deposition date: 2019-03-25, release date: 2019-05-29, Last modification date: 2023-10-11)

• Primary citation: Yang, J.,Horton, J.R.,Li, J.,Huang, Y.,Zhang, X.,Blumenthal, R.M.,Cheng, X.; Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine.; Nucleic Acids Res., 47:8375-8387, 2019; PubMed: 31081034; DOI: 10.1093/nar/gkz381

Experimental method

X-RAY DIFFRACTION (1.699 Å)