7XI3

Crystal Structure of the NPAS4-ARNT2 heterodimer in complex with DNA

Summary for 7XI3

• Entry DOI: 10.2210/pdb7xi3/pdb
• Descriptor: Aryl hydrocarbon receptor nuclear translocator 2, Neuronal PAS domain protein 4, DNA (5'-D(P*GP*GP*AP*GP*GP*TP*CP*GP*TP*GP*AP*GP*TP*GP*AP*T)-3'), ... (4 entities in total)
• Functional Keywords: transcription-dna complex, transcription/dna
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 4
• Total formula weight: 92323.42

Authors

Sun, X.N.,Jing, L.Q.,Li, F.W.,Wu, D.L. (deposition date: 2022-04-11, release date: 2022-11-02, Last modification date: 2023-11-29)

• Primary citation: Sun, X.,Jing, L.,Li, F.,Zhang, M.,Diao, X.,Zhuang, J.,Rastinejad, F.,Wu, D.; Structures of NPAS4-ARNT and NPAS4-ARNT2 heterodimers reveal new dimerization modalities in the bHLH-PAS transcription factor family.; Proc.Natl.Acad.Sci.USA, 119:e2208804119-e2208804119, 2022; PubMed: 36343253; DOI: 10.1073/pnas.2208804119

Experimental method

X-RAY DIFFRACTION (4.274 Å)