8PQ2
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![BU of 8pq2 by Molmil](/molmil-images/mine/8pq2) | XBB 1.0 RBD bound to P4J15 (Local) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, P4J15 Fragment Antigen-Binding Heavy Chain, P4J15 Fragment Antigen-Binding Light Chain, ... | Authors: | Duhoo, Y, Lau, K. | Deposit date: | 2023-07-10 | Release date: | 2023-11-01 | Last modified: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (3.85 Å) | Cite: | Broadly potent anti-SARS-CoV-2 antibody shares 93% of epitope with ACE2 and provides full protection in monkeys. J Infect, 87, 2023
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8PSD
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![BU of 8psd by Molmil](/molmil-images/mine/8psd) | SARS-CoV-2 XBB 1.0 closed conformation. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Duhoo, Y, Lau, K. | Deposit date: | 2023-07-13 | Release date: | 2023-11-01 | Last modified: | 2023-12-06 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Broadly potent anti-SARS-CoV-2 antibody shares 93% of epitope with ACE2 and provides full protection in monkeys. J Infect, 87, 2023
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7GEF
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![BU of 7gef by Molmil](/molmil-images/mine/7gef) | Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with BEN-DND-93268d01-11 (Mpro-x11428) | Descriptor: | 3C-like proteinase, DIMETHYL SULFOXIDE, N-(4-methylpyridin-3-yl)-2-(piperidin-1-yl)acetamide | Authors: | Fearon, D, Aimon, A, Aschenbrenner, J.C, Balcomb, B.H, Bertram, F.K.R, Brandao-Neto, J, Dias, A, Douangamath, A, Dunnett, L, Godoy, A.S, Gorrie-Stone, T.J, Koekemoer, L, Krojer, T, Lithgo, R.M, Lukacik, P, Marples, P.G, Mikolajek, H, Nelson, E, Owen, C.D, Powell, A.J, Rangel, V.L, Skyner, R, Strain-Damerell, C.M, Thompson, W, Tomlinson, C.W.E, Wild, C, Walsh, M.A, von Delft, F. | Deposit date: | 2023-08-11 | Release date: | 2023-11-08 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.18 Å) | Cite: | Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors. Science, 382, 2023
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7XQS
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![BU of 7xqs by Molmil](/molmil-images/mine/7xqs) | The structure of FLA-K*00701/KP-CoV-9 | Descriptor: | Beta-2-microglobulin, MHC class I antigen alpha chain, peptide from Spike glycoprotein | Authors: | Qiao, P.W, Yue, C, Peng, W.Y, Liu, K.F, Huo, S.T, Zhang, D, Chai, Y, Qi, J.X, Sun, Z.Y, Gao, G.F, Liu, W.J, Wu, G.Z. | Deposit date: | 2022-05-08 | Release date: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Analysis of the characteristics of feline major histocompatibility complex class I molecules cross-presenting coronavirus peptides To Be Published
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8BG2
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![BU of 8bg2 by Molmil](/molmil-images/mine/8bg2) | |
8BG3
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![BU of 8bg3 by Molmil](/molmil-images/mine/8bg3) | |
8BG4
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![BU of 8bg4 by Molmil](/molmil-images/mine/8bg4) | |
8BG5
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![BU of 8bg5 by Molmil](/molmil-images/mine/8bg5) | |
8BG6
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![BU of 8bg6 by Molmil](/molmil-images/mine/8bg6) | SARS-CoV-2 S protein in complex with pT1644 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, pT1644 Fab heavy chain, ... | Authors: | Stroeh, L, Hansen, G, Vollmer, B, Krey, T, Benecke, T, Gruenewald, K. | Deposit date: | 2022-10-27 | Release date: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (4.11 Å) | Cite: | Activity of broadly neutralizing antibodies against sarbecoviruses: a trade-off between SARS-CoV-2 variants and distant coronaviruses? To be published
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8BG8
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![BU of 8bg8 by Molmil](/molmil-images/mine/8bg8) | SARS-CoV-2 S protein in complex with pT1696 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, pT1696 Fab heavy chain, ... | Authors: | Hansen, G, Benecke, T, Vollmer, B, Gruenewald, K, Krey, T. | Deposit date: | 2022-10-27 | Release date: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.64 Å) | Cite: | Activity of broadly neutralizing antibodies against sarbecoviruses: a trade-off between SARS-CoV-2 variants and distant coronaviruses? To be published
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8HES
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![BU of 8hes by Molmil](/molmil-images/mine/8hes) | Crystal structure of SARS-CoV-2 RBD and NIV-10 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NIV-10 Fab H-chain, NIV-10 Fab L-chain, ... | Authors: | Moriyama, S, Anraku, Y, Taminishi, S, Adachi, Y, Kuroda, D, Higuchi, Y, Kotaki, R, Tonouchi, K, Yumoto, K, Suzuki, T, Kita, S, Someya, T, Fukuhara, H, Kuroda, Y, Yamamoto, T, Onodera, T, Fukushi, S, Maeda, K, Nakamura-Uchiyama, F, Hashiguchi, T, Hoshino, A, Maenaka, K, Takahashi, Y. | Deposit date: | 2022-11-08 | Release date: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural delineation and computational design of SARS-CoV-2-neutralizing antibodies against Omicron subvariants. Nat Commun, 14, 2023
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7TPI
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![BU of 7tpi by Molmil](/molmil-images/mine/7tpi) | SARS-CoV-2 E406W mutant Spike ectodomain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Addetia, A, Veesler, D. | Deposit date: | 2022-01-25 | Release date: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | SARS-CoV-2 E406W mutant Spike ectodomain To Be Published
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8F4P
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8IX3
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![BU of 8ix3 by Molmil](/molmil-images/mine/8ix3) | Cryo-EM structure of SARS-CoV-2 BA.4/5 spike protein in complex with 1G11 (local refinement) | Descriptor: | BA.4/5 variant spike protein, heavy chain of 1G11, light chain of 1G11 | Authors: | Sun, H, Jiang, Y, Zheng, Z, Zheng, Q, Li, S. | Deposit date: | 2023-03-31 | Release date: | 2023-11-15 | Last modified: | 2023-12-13 | Method: | ELECTRON MICROSCOPY (3.98 Å) | Cite: | Structural basis for broad neutralization of human antibody against Omicron sublineages and evasion by XBB variant. J.Virol., 97, 2023
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8U1T
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![BU of 8u1t by Molmil](/molmil-images/mine/8u1t) | SARS-CoV-2 Envelope Protein Transmembrane Domain: Dimeric Structure Determined by Solid-State NMR | Descriptor: | Envelope small membrane protein | Authors: | Zhang, R, Qin, H, Prasad, R, Fu, R, Zhou, H.X, Cross, T. | Deposit date: | 2023-09-02 | Release date: | 2023-11-15 | Last modified: | 2024-05-15 | Method: | SOLID-STATE NMR | Cite: | Dimeric Transmembrane Structure of the SARS-CoV-2 E Protein. Commun Biol, 6, 2023
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8U28
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![BU of 8u28 by Molmil](/molmil-images/mine/8u28) | |
8FIG
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![BU of 8fig by Molmil](/molmil-images/mine/8fig) | |
8SQ9
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![BU of 8sq9 by Molmil](/molmil-images/mine/8sq9) | SARS-CoV-2 replication-transcription complex bound to nsp9 and UMPCPP, as a pre-catalytic NMPylation intermediate | Descriptor: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]uridine, MAGNESIUM ION, Non-structural protein 7, ... | Authors: | Small, G.I, Darst, S.A, Campbell, E.A. | Deposit date: | 2023-05-04 | Release date: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain. Mol.Cell, 83, 2023
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8SQJ
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![BU of 8sqj by Molmil](/molmil-images/mine/8sqj) | SARS-CoV-2 replication-transcription complex bound to RNA-nsp9, as a noncatalytic RNA-nsp9 binding mode | Descriptor: | 5'-O-[(R)-hydroxy(thiophosphonooxy)phosphoryl]guanosine, MAGNESIUM ION, Non-structural protein 7, ... | Authors: | Small, G.I, Darst, S.A, Campbell, E.A. | Deposit date: | 2023-05-04 | Release date: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain. Mol.Cell, 83, 2023
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8SQK
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![BU of 8sqk by Molmil](/molmil-images/mine/8sqk) | SARS-CoV-2 replication-transcription complex bound to RNA-nsp9 and GDP-betaS, as a pre-catalytic deRNAylation/mRNA capping intermediate | Descriptor: | 5'-O-[(R)-hydroxy(thiophosphonooxy)phosphoryl]guanosine, MAGNESIUM ION, Non-structural protein 7, ... | Authors: | Small, G.I, Darst, S.A, Campbell, E.A. | Deposit date: | 2023-05-04 | Release date: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain. Mol.Cell, 83, 2023
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8X1H
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8I4S
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![BU of 8i4s by Molmil](/molmil-images/mine/8i4s) | the complex structure of SARS-CoV-2 Mpro with D8 | Descriptor: | 3-(4-fluoranyl-3-methyl-phenyl)-2-(2-methylpropyl)-5,6,7-tris(oxidanyl)quinazolin-4-one, ORF1a polyprotein | Authors: | Lu, M. | Deposit date: | 2023-01-21 | Release date: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery of quinazolin-4-one-based non-covalent inhibitors targeting the severe acute respiratory syndrome coronavirus 2 main protease (SARS-CoV-2 M pro ). Eur.J.Med.Chem., 257, 2023
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8J1T
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8J1V
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8T5P
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![BU of 8t5p by Molmil](/molmil-images/mine/8t5p) | |