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coronavirus
Coronavirus, 2020. Modified from the original illustration by David S. Goodsell@RCSB PDB

The recent outbreak of the Novel Coronavirus disease (COVID-19) is a serious threat to people all over the world. In order to understand and develop an effective drug against this virus (Severe Acute Respiratory Syndrome Coronavirus 2: SARS-CoV-2), structural work on the related proteins has already started and the resultant entries are accumulating in the PDB. PDBj provides a portal page for the COVID-19 related entries for our users. New entries will be added simultaneously with the public release from the wwPDB.

An explanation article covering one of the proteins of this virus is available on the "Molecules of the Month" page below:

The tab "All entries" contains all PDB IDs, in case you want to check all independent entries, including group depositions by the same authors. The "Repr. entries" tab contains only representative PDB entries with the highest resolution, excluding duplicate entries with 100% amino acid sequence identitiy, even if they contain a different ligand. Finally, the "Latest entries" tab contains the latest entries released this week.

Created: 2020-03-11 (last edited: 3 days ago)2020-10-28
All entries (509)Repr. entries (215)Latest entries (9)
7D1M
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CRYSTAL STRUCTURE OF THE SARS-COV-2 MAIN PROTEASE COMPLEXED WITH GC376
Descriptor:3C-like proteinase, (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, DIMETHYL SULFOXIDE
Authors:Fu, L.F., Gilski, M., Shabalin, I., Gao, G.F., Qi, J.X.
Deposit date:2020-09-14
Release date:2020-10-28
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:CRYSTAL STRUCTURE OF THE SARS-CoV-2 MAIN PROTEASE COMPLEXED WITH GC376
To Be Published
7KG3
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CRYSTAL STRUCTURE OF COV-2 NSP3 MACRODOMAIN
Descriptor:Non-structural protein 3, MALONATE ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
Authors:Arvai, A., Brosey, C.A., Link, T., Jones, D.E., Ahmed, Z., Tainer, J.A.
Deposit date:2020-10-15
Release date:2020-10-28
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors
To Be Published
7KFI
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SARS-COV-2 MAIN PROTEASE IMMATURE FORM - APO STRUCTURE
Descriptor:Main protease, DIMETHYL SULFOXIDE, DI(HYDROXYETHYL)ETHER
Authors:Noske, G.D., Nakamura, A.M., Gawriljuk, V.O., Lima, G.A.M., Zeri, A.C.M., Nascimento, A.F.Z., Oliva, G., Godoy, A.S.
Deposit date:2020-10-14
Release date:2020-10-28
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:SARS-CoV-2 Main protease immature form - apo structure
To Be Published
7KHP
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ACYL-ENZYME INTERMEDIATE STRUCTURE OF SARS-COV-2 MPRO IN COMPLEX WITH ITS C-TERMINAL AUTOPROCESSING SEQUENCE.
Descriptor:3C-like proteinase, DIMETHYL SULFOXIDE
Authors:Lee, J., Worrall, L.J., Paetzel, M., Strynadka, N.C.J.
Deposit date:2020-10-21
Release date:2020-10-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystallographic structure of wild-type SARS-CoV-2 Main Protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site
To Be Published
7JJC
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CRYSTAL STRUCTURE OF NEUROPILIN-1 B1 DOMAIN IN COMPLEX WITH SARS-COV-2 S1 C-END RULE (CENDR) PEPTIDE
Descriptor:Neuropilin-1, Spike glycoprotein, DI(HYDROXYETHYL)ETHER, ...
Authors:Chen, K.-E., Collins, B.M.
Deposit date:2020-07-25
Release date:2020-10-28
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Neuropilin-1 is a host factor for SARS-CoV-2 infection
Science, 2020
7AKU
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STRUCTURE OF SARS-COV-2 MAIN PROTEASE BOUND TO CALPEPTIN.
Descriptor:Replicase polyprotein 1ab, Calpeptin, CHLORIDE ION
Authors:Guenther, S., Reinke, P., Oberthuer, D., Yefanov, O., Gelisio, L., Ginn, H., Lieske, J., Domaracky, M., Brehm, W., Rahmani Mashour, A., White, T.A., Knoska, J., Pena Esperanza, G., Koua, F., Tolstikova, A., Groessler, M., Fischer, P., Hennicke, V., Fleckenstein, H., Trost, F., Galchenkova, M., Gevorkov, Y., Li, C., Awel, S., Paulraj, L.X., Ullah, N., Falke, S., Alves Franca, B., Schwinzer, M., Brognaro, H., Werner, N., Perbandt, M., Tidow, H., Seychell, B., Beck, T., Meier, S., Doyle, J.J., Giseler, H., Melo, D., Dunkel, I., Lane, T.J., Peck, A., Saouane, S., Hakanpaeae, J., Meyer, J., Noei, H., Gribbon, P., Ellinger, B., Kuzikov, M., Wolf, M., Zhang, L., Ehrt, C., Pletzer-Zelgert, J., Wollenhaupt, J., Feiler, C., Weiss, M., Schulz, E.C., Mehrabi, P., Norton-Baker, B., Schmidt, C., Lorenzen, K., Schubert, R., Han, H., Chari, A., Fernandez Garcia, Y., Turk, D., Hilgenfeld, R., Rarey, M., Zaliani, A., Chapman, H.N., Pearson, A., Betzel, C., Meents, A.
Deposit date:2020-10-02
Release date:2020-10-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of SARS-CoV-2 Main Protease bound to Calpeptin
To Be Published
7KFJ
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SARS-COV-2 MAIN PROTEASE IMMATURE FORM - FRAGMENT BBV-136614527
Descriptor:Main protease, DIMETHYL SULFOXIDE, DI(HYDROXYETHYL)ETHER, ...
Authors:Noske, G.D., Nakamura, A.M., Gawriljuk, V.O., Lima, G.A.M., Zeri, A.C.M., Nascimento, A.F.Z., Oliva, G., Godoy, A.S.
Deposit date:2020-10-14
Release date:2020-10-28
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:SARS-CoV-2 Main protease immature form - fragment BBV-136614527
To Be Published
7K9Z
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CRYSTAL STRUCTURE OF SARS-COV-2 RECEPTOR BINDING DOMAIN IN COMPLEX WITH THE FAB FRAGMENTS OF NEUTRALIZING ANTIBODIES 298 AND 52
Descriptor:52 Fab Heavy Chain, 52 Fab Light Chain, 298 Fab Light Chain, ...
Authors:Newton, J.C., Kucharska, I., Rujas, E., Cui, H., Julien, J.P.
Deposit date:2020-09-29
Release date:2020-10-28
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Multivalency transforms SARS-CoV-2 antibodies into broad and ultrapotent neutralizers
Biorxiv, 2020
7ACT
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THE SARS-COV-2 NUCLEOCAPSID PHOSPHOPROTEIN N-TERMINAL DOMAIN IN COMPLEX WITH 10MER SSRNA
Descriptor:Nucleoprotein, ssRNA
Authors:Veverka, V.
Deposit date:2020-09-11
Release date:2020-10-28
Method:SOLUTION NMR
Cite:The SARS-CoV-2 nucleocapsid phosphoprotein N-terminal domain in complex with 10mer ssRNA
To Be Published
170383
PDB entries from 2020-10-28