8SQ9
SARS-CoV-2 replication-transcription complex bound to nsp9 and UMPCPP, as a pre-catalytic NMPylation intermediate
Summary for 8SQ9
Entry DOI | 10.2210/pdb8sq9/pdb |
EMDB information | 40699 |
Descriptor | RNA-directed RNA polymerase, Non-structural protein 8, Non-structural protein 7, ... (10 entities in total) |
Functional Keywords | rtc, nsp12, nsp9, niran, sars-cov-2, nmpylation, umpcpp, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 More |
Total number of polymer chains | 7 |
Total formula weight | 202132.44 |
Authors | |
Primary citation | Small, G.I.,Fedorova, O.,Olinares, P.D.B.,Chandanani, J.,Banerjee, A.,Choi, Y.J.,Molina, H.,Chait, B.T.,Darst, S.A.,Campbell, E.A. Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain. Mol.Cell, 83:3921-3930.e7, 2023 Cited by PubMed: 37890482DOI: 10.1016/j.molcel.2023.10.001 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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