8WRH

SARS-CoV-2 XBB.1.5.70 in complex with ACE2

Summary for 8WRH

Entry DOI	10.2210/pdb8wrh/pdb
EMDB information	37776
Descriptor	Angiotensin-converting enzyme 2, Spike protein S2', 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	sars-cov-2, xbb.1.5.70, rbd, ace2, viral protein/hydrolase, viral protein-hydrolase complex
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	115509.49
Authors	Feng, L.L.,Feng, L.L. (deposition date: 2023-10-14, release date: 2023-11-29, Last modification date: 2024-03-20)
Primary citation	Jian, F.,Feng, L.,Yang, S.,Yu, Y.,Wang, L.,Song, W.,Yisimayi, A.,Chen, X.,Xu, Y.,Wang, P.,Yu, L.,Wang, J.,Liu, L.,Niu, X.,Wang, J.,Xiao, T.,An, R.,Wang, Y.,Gu, Q.,Shao, F.,Jin, R.,Shen, Z.,Wang, Y.,Wang, X.,Cao, Y. Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455-456 synergistically enhances antibody evasion and ACE2 binding. Plos Pathog., 19:e1011868-e1011868, 2023 Cited by PubMed: 38117863 DOI: 10.1371/journal.ppat.1011868 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.08 Å)

Structure validation