Author results

1W0M
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TRIOSEPHOSPHATE ISOMERASE FROM THERMOPROTEUS TENAX
分子名称:TRIOSEPHOSPHATE ISOMERASE, PHOSPHATE ION
著者Walden, H., Taylor, G., Lorentzen, E., Pohl, E., Lilie, H., Schramm, A., Knura, T., Stubbe, K., Tjaden, B., Hensel, R.
登録日2004-06-08
公開日2004-09-09
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and Function of a Regulated Archaeal Triosephosphate Isomerase Adapted to High Temperature
J.Mol.Biol., 342, 2004
1HG3
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CRYSTAL STRUCTURE OF TETRAMERIC TIM FROM PYROCOCCUS WOESEI.
分子名称:TRIOSEPHOSPHATE ISOMERASE, 3-PHOSPHONOPROPANOIC ACID
著者Walden, H., Bell, G.S., Russell, R.J.M., Siebers, B., Hensel, R., Taylor, G.L.
登録日2000-12-12
公開日2001-03-07
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Tiny Tim: A Small, Tetrameric, Hyperthermostable Triosephosphate Isomerase
J.Mol.Biol., 306, 2001
1R4M
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APPBP1-UBA3-NEDD8, AN E1-UBIQUITIN-LIKE PROTEIN COMPLEX
分子名称:amyloid beta precursor protein-binding protein 1, ubiquitin-activating enzyme E1C, Ubiquitin-like protein NEDD8, ...
著者Walden, H., Podgorski, M.S., Holton, J.M., Schulman, B.A.
登録日2003-10-07
公開日2003-12-23
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.
Mol.Cell, 12, 2003
1R4N
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APPBP1-UBA3-NEDD8, AN E1-UBIQUITIN-LIKE PROTEIN COMPLEX WITH ATP
分子名称:amyloid beta precursor protein-binding protein 1, ubiquitin-activating enzyme E1C, Ubiquitin-like protein NEDD8, ...
著者Walden, H., Podgorski, M.S., Holton, J.M., Schulman, B.A.
登録日2003-10-07
公開日2003-12-23
最終更新日2017-02-01
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.
Mol.Cell, 12, 2003
1YOV
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INSIGHTS INTO THE UBIQUITIN TRANSFER CASCADE FROM THE REFINED STRUCTURE OF THE ACTIVATING ENZYME FOR NEDD8
分子名称:Amyloid protein-binding protein 1, Ubiquitin-activating enzyme E1C, ZINC ION
著者Walden, H., Podgorski, M.S., Schulman, B.A.
登録日2005-01-28
公開日2005-03-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Insights into the Ubiquitin Transfer Cascade from the refined structure of the activating enzyme for NEDD8
Nature, 422, 2003
6N13
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UBCH7-UB COMPLEX WITH R0RBR PARKIN AND PHOSPHOUBIQUITIN
分子名称:E3 ubiquitin-protein ligase parkin, ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ...
著者Condos, T.E.C., Dunkerley, K.M., Freeman, E.A., Barber, K.R., Aguirre, J.D., Chaugule, V.K., Xiao, Y., Konermann, L., Walden, H., Shaw, G.S.
登録日2018-11-08
公開日2018-11-28
最終更新日2018-12-12
実験手法SOLUTION NMR
主引用文献Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation.
EMBO J., 37, 2018
1W37
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2-KETO-3-DEOXYGLUCONATE(KDG) ALDOLASE OF SULFOLOBUS SOLFATARICUS
分子名称:2-KETO-3-DEOXY GLUCONATE ALDOLASE, GLYCEROL, SODIUM ION
著者Theodossis, A., Walden, H., Westwick, E.J., Connaris, H., Lamble, H.J., Hough, D.W., Danson, M.J., Taylor, G.L.
登録日2004-07-13
公開日2004-09-02
最終更新日2018-03-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structural basis for substrate promiscuity in 2-keto-3-deoxygluconate aldolase from the Entner-Doudoroff pathway in Sulfolobus solfataricus.
J. Biol. Chem., 279, 2004
1W3I
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SULFOLOBUS SOLFATARICUS 2-KETO-3-DEOXYGLUCONATE (KDG) ALDOLASE COMPLEX WITH PYRUVATE
分子名称:2-KETO-3-DEOXY GLUCONATE ALDOLASE, PYRUVIC ACID, GLYCEROL
著者Theodossis, A., Walden, H., Westwick, E.J., Connaris, H., Lamble, H.J., Hough, D.W., Danson, M.J., Taylor, G.L.
登録日2004-07-15
公開日2004-09-02
最終更新日2018-03-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The structural basis for substrate promiscuity in 2-keto-3-deoxygluconate aldolase from the Entner-Doudoroff pathway in Sulfolobus solfataricus.
J. Biol. Chem., 279, 2004
1W3N
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SULFOLOBUS SOLFATARICUS 2-KETO-3-DEOXYGLUCONATE (KDG) ALDOLASE COMPLEX WITH D-KDG
分子名称:2-KETO-3-DEOXY GLUCONATE ALDOLASE, 3-DEOXY-D-ARABINO-HEXONIC ACID, GLYCEROL
著者Theodossis, A., Walden, H., Westwick, E.J., Connaris, H., Lamble, H.J., Hough, D.W., Danson, M.J., Taylor, G.L.
登録日2004-07-17
公開日2004-09-02
最終更新日2018-03-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structural basis for substrate promiscuity in 2-keto-3-deoxygluconate aldolase from the Entner-Doudoroff pathway in Sulfolobus solfataricus.
J. Biol. Chem., 279, 2004
1W3T
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SULFOLOBUS SOLFATARICUS 2-KETO-3-DEOXYGLUCONATE (KDG) ALDOLASE COMPLEX WITH D-KDGAL, D-GLYCERALDEHYDE AND PYRUVATE
分子名称:2-KETO-3-DEOXY GLUCONATE ALDOLASE, 3-DEOXY-D-LYXO-HEXONIC ACID, PYRUVIC ACID, ...
著者Theodossis, A., Walden, H., Westwick, E.J., Connaris, H., Lamble, H.J., Hough, D.W., Danson, M.J., Taylor, G.L.
登録日2004-07-19
公開日2004-09-02
最終更新日2018-03-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structural basis for substrate promiscuity in 2-keto-3-deoxygluconate aldolase from the Entner-Doudoroff pathway in Sulfolobus solfataricus.
J. Biol. Chem., 279, 2004
1YN6
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CRYSTAL STRUCTURE OF A MOUSE MHC CLASS I PROTEIN, H2-DB, IN COMPLEX WITH A PEPTIDE FROM THE INFLUENZA A ACID POLYMERASE
分子名称:H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, ...
著者Turner, S.J., Kedzierska, K., Komodromou, H., La Gruta, N.L., Dunstone, M.A., Webb, A.I., Webby, R., Walden, H., Xie, W., McCluskey, J., Purcell, A.W., Rossjohn, J., Doherty, P.C.
登録日2005-01-23
公開日2005-06-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations
Nat.Immunol., 6, 2005
1YN7
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CRYSTAL STRUCTURE OF A MOUSE MHC CLASS I PROTEIN, H2-DB, IN COMPLEX WITH A MUTATED PEPTIDE (R7A) OF THE INFLUENZA A ACID POLYMERASE
分子名称:H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, ...
著者Turner, S.J., Kedzierska, K., Komodromou, H., La Gruta, N.L., Dunstone, M.A., Webb, A.I., Webby, R., Walden, H., Xie, W., McCluskey, J., Purcell, A.W., Rossjohn, J., Doherty, P.C.
登録日2005-01-24
公開日2005-06-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations
Nat.Immunol., 6, 2005
1ZFN
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STRUCTURAL ANALYSIS OF ESCHERICHIA COLI THIF
分子名称:Adenylyltransferase thiF, ZINC ION, ADENOSINE-5'-TRIPHOSPHATE
著者Duda, D.M., Walden, H., Sfondouris, J., Schulman, B.A.
登録日2005-04-20
公開日2005-06-14
最終更新日2014-11-19
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural Analysis of Escherichia Coli ThiF.
J.Mol.Biol., 349, 2005
1ZKM
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STRUCTURAL ANALYSIS OF ESCHERICHIA COLI THIF
分子名称:Adenylyltransferase thiF, ZINC ION
著者Duda, D.M., Walden, H., Sfondouris, J., Schulman, B.A.
登録日2005-05-03
公開日2005-06-14
最終更新日2014-11-12
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural Analysis of Escherichia Coli ThiF.
J.Mol.Biol., 349, 2005
3HTM
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STRUCTURES OF SPOP-SUBSTRATE COMPLEXES: INSIGHTS INTO MOLECULAR ARCHITECTURES OF BTB-CUL3 UBIQUITIN LIGASES: SPOPBTB/3-BOX
分子名称:Speckle-type POZ protein
著者Zhuang, M., Walden, H., Schulman, B.A.
登録日2009-06-11
公開日2009-10-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
3K1L
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CRYSTAL STRUCTURE OF FANCL
分子名称:Fancl, ZINC ION, MALTOSE, ...
著者Cole, A.R., Walden, H.
登録日2009-09-28
公開日2010-02-16
最終更新日2014-02-12
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The structure of the catalytic subunit FANCL of the Fanconi anemia core complex
Nat.Struct.Mol.Biol., 17, 2010
3ZQS
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HUMAN FANCL CENTRAL DOMAIN
分子名称:E3 UBIQUITIN-PROTEIN LIGASE FANCL, PROLINE, HEXAETHYLENE GLYCOL, ...
著者Hodson, C., Cole, A.R., Purkiss-Trew, A., Walden, H.
登録日2011-06-10
公開日2011-07-20
最終更新日2011-09-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Analysis of Human Fancl, the E3 Ligase in the Fanconi Anemia Pathway.
J.Biol.Chem., 286, 2011
4CCG
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STRUCTURE OF AN E2-E3 COMPLEX
分子名称:UBIQUITIN-CONJUGATING ENZYME E2 T, E3 UBIQUITIN-PROTEIN LIGASE FANCL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Hodson, C., Purkiss, A., Walden, H.
登録日2013-10-22
公開日2014-01-08
最終更新日2014-02-19
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the Human Fancl Ring-Ube2T Complex Reveals Determinants of Cognate E3-E2 Selection.
Structure, 22, 2014
5C1Z
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PARKIN (UBLR0RBR)
分子名称:E3 ubiquitin-protein ligase parkin, ZINC ION, SULFATE ION, ...
著者kumar, A., Aguirre, J.D., Condos, T.E.C., Martinez-Torres, R.J., Chaugule, V.K., Toth, R., Sundaramoorthy, R., Mercier, P., Knebel, A., Spratt, D.E., Barber, K.R., Shaw, G.S., Walden, H.
登録日2015-06-15
公開日2015-07-29
最終更新日2015-10-28
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
5C23
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PARKIN (S65DUBLR0RBR)
分子名称:E3 ubiquitin-protein ligase parkin, ZINC ION, GLYCEROL, ...
著者Kumar, A., Aguirre, J.D., Condos, T.E.C., Martinez-Torres, R.J., Chaugule, V.K., Toth, R., Sundaramoorthy, R., Mercier, P., Knebel, A., Spratt, D.E., Barber, K.R., Shaw, G.S., Walden, H.
登録日2015-06-15
公開日2015-07-29
最終更新日2015-10-28
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis.
Embo J., 34, 2015
5N2W
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WT-PARKIN AND PUB COMPLEX
分子名称:E3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, ZINC ION, ...
著者Kumar, A., Chaugule, V.K., Johnson, C., Toth, R., Sundaramoorthy, R., Knebel, A., Walden, H.
登録日2017-02-08
公開日2017-04-19
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.
Nat. Struct. Mol. Biol., 24, 2017
5N38
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S65DPARKIN AND PUB COMPLEX
分子名称:E3 ubiquitin-protein ligase parkin,E3 ubiquitin-protein ligase parkin, Polyubiquitin-B, DI(HYDROXYETHYL)ETHER, ...
著者Kumar, A., Chaugule, V.K., Johnson, C., Toth, R., Sundaramoorthy, R., Knebel, A., Walden, H.
登録日2017-02-08
公開日2017-04-19
最終更新日2018-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.
Nat. Struct. Mol. Biol., 24, 2017
5NGZ
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UBE2T IN COMPLEX WITH FRAGMENT EM04
分子名称:Ubiquitin-conjugating enzyme E2 T, 1-(1,3-benzothiazol-2-yl)methanamine
著者Morreale, F.E., Bortoluzzi, A., Chaugule, V.K., Arkinson, C., Walden, H., Ciulli, A.
登録日2017-03-21
公開日2017-05-03
最終更新日2017-05-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Allosteric Targeting of the Fanconi Anemia Ubiquitin-Conjugating Enzyme Ube2T by Fragment Screening.
J. Med. Chem., 60, 2017
5OJJ
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CRYSTAL STRUCTURE OF THE ZN-BOUND UBIQUITIN-CONJUGATING ENZYME UBE2T
分子名称:Ubiquitin-conjugating enzyme E2 T, ACETATE ION, ZINC ION, ...
著者Morreale, F.E., Testa, A., Chaugule, V.K., Bortoluzzi, A., Ciulli, A., Walden, H.
登録日2017-07-21
公開日2017-10-04
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Mind the Metal: A Fragment Library-Derived Zinc Impurity Binds the E2 Ubiquitin-Conjugating Enzyme Ube2T and Induces Structural Rearrangements.
J. Med. Chem., 60, 2017
6R75
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CRYSTAL STRUCTURE OF HUMAN UBE2T E54R MUTANT
分子名称:Ubiquitin-conjugating enzyme E2 T
著者Chaugule, V.K., Rennie, M.L., Walden, H., Arkinson, C., Kamarainen, O., Toth, R.
登録日2019-03-28
公開日2019-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of human Ube2T E54R mutant
To Be Published
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