APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex

Summary for 1R4M

Descriptoramyloid beta precursor protein-binding protein 1, ubiquitin-activating enzyme E1C, Ubiquitin-like protein NEDD8, ... (4 entities in total)
Functional Keywordscell cycle
Biological sourceHomo sapiens (human)
Cellular locationCell membrane Q13564
Nucleus Q15843
Total number of polymer chains12
Total molecular weight467453.03
Walden, H.,Podgorski, M.S.,Holton, J.M.,Schulman, B.A. (deposition date: 2003-10-07, release date: 2003-12-23, Last modification date: 2011-07-13)
Primary citation
Walden, H.,Podgorski, M.S.,Huang, D.T.,Miller, D.W.,Howard, R.J.,Minor, D.L.,Holton, J.M.,Schulman, B.A.
The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.
Mol.Cell, 12:1427-1437, 2003
PubMed: 14690597 (PDB entries with the same primary citation)
DOI: 10.1016/S1097-2765(03)00452-0
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers273.3%5.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution