1R4M
APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E, G | amyloid beta precursor protein-binding protein 1 | polymer | 529 | 59829.7 | 4 | UniProt (Q13564) Pfam (PF00899) In PDB | Homo sapiens (human) | APPBP1 |
2 | B, D, F, H | ubiquitin-activating enzyme E1C | polymer | 431 | 48394.2 | 4 | UniProt (Q8TBC4) Pfam (PF00899) Pfam (PF08825) In PDB | Homo sapiens (human) | UBA3 |
3 | I, J, K, L | Ubiquitin-like protein NEDD8 | polymer | 76 | 8574.0 | 4 | UniProt (Q15843) Pfam (PF00240) In PDB | Homo sapiens (human) | NEDD8 |
4 | J, F, H | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
Sequence modifications
A, C, E, G: 1 - 534 (UniProt: Q13564)
B, D, F, H: 12 - 918 (UniProt: Q8TBC4)
PDB | External Database | Details |
---|---|---|
- | Asn 254 | deletion |
- | Glu 255 | deletion |
- | Asn 256 | deletion |
- | Gly 257 | deletion |
- | Ala 258 | deletion |
PDB | External Database | Details |
---|---|---|
Ala 216 | Cys 237 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 467191.4 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 261.6 | |
All* | Total formula weight | 467453.0 |