APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex with ATP

Summary for 1R4N

Descriptoramyloid beta precursor protein-binding protein 1, ubiquitin-activating enzyme E1C, Ubiquitin-like protein NEDD8, ... (5 entities in total)
Functional Keywordscell cycle
Biological sourceHomo sapiens (human)
Cellular locationCell membrane  Q13564
Nucleus  Q15843
Total number of polymer chains12
Total molecular weight469481.76
Walden, H.,Podgorski, M.S.,Holton, J.M.,Schulman, B.A. (deposition date: 2003-10-07, release date: 2003-12-23, Last modification date: 2017-02-01)
Primary citation
Walden, H.,Podgorski, M.S.,Huang, D.T.,Miller, D.W.,Howard, R.J.,Minor, D.L.,Holton, J.M.,Schulman, B.A.
The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.
Mol.Cell, 12:1427-1437, 2003
PubMed: 14690597 (PDB entries with the same primary citation)
DOI: 10.1016/S1097-2765(03)00452-0
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers365.5%6.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution