1R4N

APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex with ATP

Summary for 1R4N

• Entry DOI: 10.2210/pdb1r4n/pdb
• Related: 1R4M
• Descriptor: amyloid beta precursor protein-binding protein 1, ubiquitin-activating enzyme E1C, Ubiquitin-like protein NEDD8, ... (5 entities in total)
• Functional Keywords: cell cycle
• Biological source: Homo sapiens (human); More
• Cellular location: Cell membrane : Q13564; Nucleus : Q15843
• Total number of polymer chains: 12
• Total formula weight: 469481.76

Authors

Walden, H.,Podgorski, M.S.,Holton, J.M.,Schulman, B.A. (deposition date: 2003-10-07, release date: 2003-12-23, Last modification date: 2023-08-23)

• Primary citation: Walden, H.,Podgorski, M.S.,Huang, D.T.,Miller, D.W.,Howard, R.J.,Minor, D.L.,Holton, J.M.,Schulman, B.A.; The structure of the APPBP1-UBA3-NEDD8-ATP complex reveals the basis for selective ubiquitin-like protein activation by an E1.; Mol.Cell, 12:1427-1437, 2003; PubMed: 14690597; DOI: 10.1016/S1097-2765(03)00452-0

Experimental method

X-RAY DIFFRACTION (3.6 Å)