1R4N
APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex with ATP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G | amyloid beta precursor protein-binding protein 1 | polymer | 529 | 59829.7 | 4 | UniProt (Q13564) Pfam (PF00899) In PDB | Homo sapiens (human) | APPBP1 |
| 2 | B, D, F, H | ubiquitin-activating enzyme E1C | polymer | 431 | 48394.2 | 4 | UniProt (Q8TBC4) Pfam (PF00899) Pfam (PF08825) In PDB | Homo sapiens (human) | UBA3 |
| 3 | I, J, K, L | Ubiquitin-like protein NEDD8 | polymer | 76 | 8574.0 | 4 | UniProt (Q15843) Pfam (PF00240) In PDB | Homo sapiens (human) | NEDD8 |
| 4 | B, D, F, H | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 4 | Chemie (ATP) | |||
| 5 | J, F, H | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
Sequence modifications
A, C, E, G: 1 - 534 (UniProt: Q13564)
B, D, F, H: 12 - 918 (UniProt: Q8TBC4)
| PDB | External Database | Details |
|---|---|---|
| - | Asn 254 | deletion |
| - | Glu 255 | deletion |
| - | Asn 256 | deletion |
| - | Gly 257 | deletion |
| - | Ala 258 | deletion |
| PDB | External Database | Details |
|---|---|---|
| Ala 150 | Cys 237 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 467191.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2290.4 | |
| All* | Total formula weight | 469481.8 |
