Author results

3V7D
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CRYSTAL STRUCTURE OF SCSKP1-SCCDC4-PSIC1 PEPTIDE COMPLEX
Descriptor:Suppressor of kinetochore protein 1, Cell division control protein 4, Protein SIC1
Authors:Tang, X., Orlicky, S., Mittag, T., Csizmok, V., Pawson, T., Forman-Kay, J., Sicheri, F., Tyers, M.
Deposit date:2011-12-20
Release date:2012-05-02
Method:X-RAY DIFFRACTION (2.306 Å)
Cite:Composite low affinity interactions dictate recognition of the cyclin-dependent kinase inhibitor Sic1 by the SCFCdc4 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 109, 2012
5DMR
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CRYSTAL STRUCTURE OF C-TERMINAL DOMAIN OF MOUSE ERF1 IN COMPLEX WITH RNASE H DOMAIN OF RT OF MOLONEY MURINE LEUKEMIA VIRUS
Descriptor:Reverse transcriptase/ribonuclease H p80, Eukaryotic peptide chain release factor subunit 1
Authors:Tang, X., Song, H.
Deposit date:2015-09-09
Release date:2016-07-06
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of suppression of host translation termination by Moloney Murine Leukemia Virus
Nat Commun, 7, 2016
5H3S
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APO FORM OF GEMIN5-WD
Descriptor:Gem-associated protein 5, GLYCEROL
Authors:Bharath, S.R., Tang, X., Song, H.
Deposit date:2016-10-27
Release date:2016-12-28
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for specific recognition of pre-snRNA by Gemin5
Cell Res., 26, 2016
5H3T
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M7G CAP BOUND TO GEMIN5-WD
Descriptor:Gem-associated protein 5, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, GLYCEROL
Authors:Bharath, S.R., Tang, X., Song, H.
Deposit date:2016-10-27
Release date:2016-12-28
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.571 Å)
Cite:Structural basis for specific recognition of pre-snRNA by Gemin5
Cell Res., 26, 2016
5H3U
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SM RNA BOUND TO GEMIN5-WD
Descriptor:Gem-associated protein 5, RNA (5'-R(*AP*AP*UP*UP*UP*UP*UP*GP*AP*C)-3'), GLYCEROL
Authors:Bharath, S.R., Tang, X., Song, H.
Deposit date:2016-10-27
Release date:2016-12-28
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.499 Å)
Cite:Structural basis for specific recognition of pre-snRNA by Gemin5
Cell Res., 26, 2016
1NEX
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CRYSTAL STRUCTURE OF SCSKP1-SCCDC4-CPD PEPTIDE COMPLEX
Descriptor:Centromere DNA-binding protein complex CBF3 subunit D, CDC4 protein, GLL(TPO)PPQSG
Authors:Orlicky, S., Tang, X., Willems, A., Tyers, M., Sicheri, F.
Deposit date:2002-12-12
Release date:2003-02-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis for Phosphodependent Substrate Selection and Orientation by the SCFCdc4 Ubiquitin Ligase
Cell(Cambridge,Mass.), 112, 2003
2C7T
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CRYSTAL STRUCTURE OF THE PLP-BOUND FORM OF BTRR, A DUAL FUNCTIONAL AMINOTRANSFERASE INVOLVED IN BUTIROSIN BIOSYNTHESIS.
Descriptor:GLUTAMINE-2-DEOXY-SCYLLO-INOSOSE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION
Authors:Popovic, B., Tang, X., Chirgadze, D.Y., Huang, F., Blundell, T.L., Spencer, J.B.
Deposit date:2005-11-29
Release date:2006-08-16
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structures of the PLP- and PMP-bound forms of BtrR, a dual functional aminotransferase involved in butirosin biosynthesis.
Proteins, 65, 2006
2C81
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CRYSTAL STRUCTURES OF THE PLP- AND PMP-BOUND FORMS OF BTRR, A DUAL FUNCTIONAL AMINOTRANSFERASE INVOLVED IN BUTIROSIN BIOSYNTHESIS.
Descriptor:GLUTAMINE-2-DEOXY-SCYLLO-INOSOSE AMINOTRANSFERASE, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE
Authors:Popovic, B., Tang, X., Chirgadze, D.Y., Huang, F., Blundell, T.L., Spencer, J.B.
Deposit date:2005-11-30
Release date:2006-08-16
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of the PLP- and PMP-bound forms of BtrR, a dual functional aminotransferase involved in butirosin biosynthesis.
Proteins, 65, 2006
2LUV
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STRUCTURE AND BINDING INTERFACE OF THE CYTOSOLIC TAILS OF AXB2 INTEGRIN
Descriptor:Integrin alpha-X
Authors:Chua, G.L., Tang, X., Patra, T.A., Tan, S.M., Bhattacharjya, S.
Deposit date:2012-06-21
Release date:2012-07-04
Method:SOLUTION NMR
Cite:Structure and Binding Interface of the Cytosolic Tails of aXb2 Integrin
To be Published
3MKS
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CRYSTAL STRUCTURE OF YEAST CDC4/SKP1 IN COMPLEX WITH AN ALLOSTERIC INHIBITOR SCF-I2
Descriptor:Suppressor of kinetochore protein 1, Cell division control protein 4, SULFATE ION, ...
Authors:Orlicky, S., Sicheri, F., Tyers, M., Tang, X.
Deposit date:2010-04-15
Release date:2010-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:An allosteric inhibitor of substrate recognition by the SCF(Cdc4) ubiquitin ligase.
Nat.Biotechnol., 28, 2010
4OWT
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STRUCTURAL BASIS OF SOSS1 COMPLEX ASSEMBLY
Descriptor:Integrator complex subunit 3, SOSS complex subunit B1, SOSS complex subunit C
Authors:Ren, W., Sun, Q., Tang, X., Song, H.
Deposit date:2014-02-03
Release date:2014-04-16
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Basis of SOSS1 Complex Assembly and Recognition of ssDNA.
Cell Rep, 6, 2014
4OWW
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STRUCTURAL BASIS OF SOSS1 IN COMPLEX WITH A 35NT SSDNA
Descriptor:DNA (5'-D(P*TP*TP*TP*TP*TP*T)-3'), Integrator complex subunit 3, SOSS complex subunit B1, ...
Authors:Ren, W., Sun, Q., Tang, X., Song, H.
Deposit date:2014-02-04
Release date:2014-04-16
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of SOSS1 Complex Assembly and Recognition of ssDNA.
Cell Rep, 6, 2014
4OWX
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STRUCTURAL BASIS OF SOSS1 IN COMPLEX WITH A 12NT SSDNA
Descriptor:DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), Integrator complex subunit 3, SOSS complex subunit B1
Authors:Ren, W., Sun, Q., Tang, X., Song, H.
Deposit date:2014-02-04
Release date:2014-04-16
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of SOSS1 Complex Assembly and Recognition of ssDNA.
Cell Rep, 6, 2014
5L75
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A PROTEIN STRUCTURE
Descriptor:Lipopolysaccharide ABC transporter, ATP-binding protein LptB, FIG000988: Predicted permease, ...
Authors:Dong, C., Dong, H., Zhang, Z., Paterson, N., Tang, X.
Deposit date:2016-06-01
Release date:2017-08-16
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Structural and functional insights into the lipopolysaccharide ABC transporter LptB2FG.
Nat Commun, 8, 2017
2ED6
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CRYSTAL STRUCTURE OF ENVELOPE PROTEIN VP28 FROM WHITE SPOT SYNDROME VIRUS (WSSV)
Descriptor:25kDa structural protein VP25
Authors:Hew, C.L., Sivaraman, J., Tang, X.H.
Deposit date:2007-02-14
Release date:2007-06-05
Last modified:2014-04-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of major envelope proteins VP26 and VP28 from white spot syndrome virus shed light on their evolutionary relationship
J.Virol., 81, 2007
5DMQ
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CRYSTAL STRUCTURE OF MOUSE ERF1 IN COMPLEX WITH REVERSE TRANSCRIPTASE (RT) OF MOLONEY MURINE LEUKEMIA VIRUS
Descriptor:Reverse transcriptase/ribonuclease H p80, Eukaryotic peptide chain release factor subunit 1
Authors:Tang, T., Song, H.
Deposit date:2015-09-09
Release date:2016-07-06
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structural basis of suppression of host translation termination by Moloney Murine Leukemia Virus
Nat Commun, 7, 2016
2P63
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SUPRAFACIAL ORIENTATION OF THE SCFCDC4 DIMER ACCOMMODATES MULTIPLE GEOMETRIES FOR SUBSTRATE UBIQUITINATION
Descriptor:Cell division control protein 4
Authors:Orlicky, S., Neculai, D., Ceccarelli, D.
Deposit date:2007-03-16
Release date:2007-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Suprafacial orientation of the SCFCdc4 dimer accommodates multiple geometries for substrate ubiquitination.
Cell(Cambridge,Mass.), 129, 2007
2P64
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D DOMAIN OF B-TRCP
Descriptor:F-box/WD repeat protein 1A, CADMIUM ION
Authors:Neculai, D., Orlicky, S., Ceccarelli, D.
Deposit date:2007-03-16
Release date:2007-06-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Suprafacial orientation of the SCFCdc4 dimer accommodates multiple geometries for substrate ubiquitination.
Cell(Cambridge,Mass.), 129, 2007
4PLJ
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HEPATITIS E VIRUS E2S DOMAIN (GENOTYPE IV) IN COMPLEX WITH A NEUTRALIZING ANTIBODY 8G12
Descriptor:Capsid protein, 8G12 light chain, 8G12 heavy chain
Authors:Tang, X.H., Li, S.W., Sivaraman, J.
Deposit date:2014-05-18
Release date:2015-04-15
Last modified:2015-05-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for the neutralization of hepatitis E virus by a cross-genotype antibody
Cell Res., 25, 2015
4PLK
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HEPATITIS E VIRUS E2S DOMAIN (GENOTYPE I) IN COMPLEX WITH A NEUTRALIZING ANTIBODY 8G12
Descriptor:Capsid protein, 8G12 light chain, 8G12 heavy chain
Authors:Tang, X.H., Li, S.W., Sivaraman, J.
Deposit date:2014-05-18
Release date:2015-04-08
Last modified:2015-05-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Structural basis for the neutralization of hepatitis E virus by a cross-genotype antibody
Cell Res., 25, 2015
1MC0
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REGULATORY SEGMENT OF MOUSE 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 2A, CONTAINING THE GAF A AND GAF B DOMAINS
Descriptor:3',5'-cyclic nucleotide phosphodiesterase 2A, CYCLIC GUANOSINE MONOPHOSPHATE
Authors:Martinez, S., Wu, A., Glavas, N., Tang, X., Turley, S., Hol, W., Beavo, J.
Deposit date:2002-08-04
Release date:2002-10-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding.
Proc.Natl.Acad.Sci.USA, 99, 2002
3GGQ
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DIMERIZATION OF HEPATITIS E VIRUS CAPSID PROTEIN E2S DOMAIN IS ESSENTIAL FOR VIRUS-HOST INTERACTION
Descriptor:Capsid protein, BROMIDE ION
Authors:Li, S.W., Tang, X.H., Seetharaman, J., Yang, C.Y., Gu, Y., Zhang, J., Du, H.L., Shih, J.W.K., Hew, C.L., Sivaraman, J., Xia, N.S.
Deposit date:2009-03-02
Release date:2009-08-25
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Dimerization of hepatitis E virus capsid protein E2s domain is essential for virus-host interaction
Plos Pathog., 5, 2009
5FHD
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STRUCTURE OF BACTEROIDES SP PIF1 COMPLEXED WITH TAILED DSDNA RESULTING IN SSDNA BOUND COMPLEX
Descriptor:Uncharacterized protein, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*CP*CP*GP*GP*GP*GP*CP*CP*GP*CP*GP*C)-3'), ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Zhou, X., Ren, W., Bharath, S.R., Song, H.
Deposit date:2015-12-22
Release date:2016-03-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Functional Insights into the Unwinding Mechanism of Bacteroides sp Pif1
Cell Rep, 14, 2016
5FHE
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CRYSTAL STRUCTURE OF BACTEROIDES PIF1 BOUND TO SSDNA
Descriptor:Uncharacterized protein, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Zhou, X., Ren, W., Bharath, S.R., Song, H.
Deposit date:2015-12-22
Release date:2016-03-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and Functional Insights into the Unwinding Mechanism of Bacteroides sp Pif1
Cell Rep, 14, 2016
5FHF
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CRYSTAL STRUCTURE OF BACTEROIDES SP PIF1 IN COMPLEX WITH ADP-ALF4
Descriptor:Uncharacterized protein, ADENOSINE-5'-DIPHOSPHATE, TETRAFLUOROALUMINATE ION
Authors:Zhou, X., Ren, W., Bharath, S.R., Song, H.
Deposit date:2015-12-22
Release date:2016-03-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and Functional Insights into the Unwinding Mechanism of Bacteroides sp Pif1
Cell Rep, 14, 2016
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