Crystal Structure of C-terminal domain of mouse eRF1 in complex with RNase H domain of RT of Moloney Murine Leukemia Virus

Summary for 5DMR

DescriptorReverse transcriptase/ribonuclease H p80, Eukaryotic peptide chain release factor subunit 1 (3 entities in total)
Functional Keywordserf1, rt, complex, hydrolase-translation complex, hydrolase/translation
Biological sourceMoloney murine leukemia virus (isolate Shinnick) (MoMLV)
Cellular locationGag-Pol polyprotein: Host cell membrane ; Lipid-anchor . Matrix protein p15: Virion . Capsid protein p30: Virion . Nucleocapsid protein p10: Virion  P03355
Cytoplasm  Q8BWY3
Total number of polymer chains2
Total molecular weight37544.23
Tang, X.,Song, H. (deposition date: 2015-09-09, release date: 2016-07-06, Last modification date: 2017-10-04)
Primary citation
Tang, X.,Zhu, Y.,Baker, S.L.,Bowler, M.W.,Chen, B.J.,Chen, C.,Hogg, J.R.,Goff, S.P.,Song, H.
Structural basis of suppression of host translation termination by Moloney Murine Leukemia Virus
Nat Commun, 7:12070-12070, 2016
PubMed: 27329342 (PDB entries with the same primary citation)
DOI: 10.1038/ncomms12070
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2742 2.4% 5.2% 0.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-14