Crystal Structure of ScSkp1-ScCdc4-pSic1 peptide complex

Summary for 3V7D

Related1NEX 3MKS
DescriptorSuppressor of kinetochore protein 1, Cell division control protein 4, Protein SIC1, ... (4 entities in total)
Functional Keywordswd 40 domain, phospho-peptide complex, e3 ubiquitin ligase, ligase, cell cycle, phospho binding protein, sic1, phosphorylation
Biological sourceSaccharomyces cerevisiae (Baker's yeast)
Total number of polymer chains5
Total molecular weight147054.61
Tang, X.,Orlicky, S.,Mittag, T.,Csizmok, V.,Pawson, T.,Forman-Kay, J.,Sicheri, F.,Tyers, M. (deposition date: 2011-12-20, release date: 2012-05-02, Last modification date: 2019-07-17)
Primary citation
Tang, X.,Orlicky, S.,Mittag, T.,Csizmok, V.,Pawson, T.,Forman-Kay, J.D.,Sicheri, F.,Tyers, M.
Composite low affinity interactions dictate recognition of the cyclin-dependent kinase inhibitor Sic1 by the SCFCdc4 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 109:3287-3292, 2012
PubMed: 22328159 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1116455109
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2112 0.3% 1.2% 2.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-11-25