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1ATZ
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BU of 1atz by Molmil
HUMAN VON WILLEBRAND FACTOR A3 DOMAIN
Descriptor: VON WILLEBRAND FACTOR
Authors:Huizinga, E.G, Gros, P.
Deposit date:1997-08-15
Release date:1998-02-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the A3 domain of human von Willebrand factor: implications for collagen binding.
Structure, 5, 1997
1D5V
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BU of 1d5v by Molmil
SOLUTION STRUCTURE OF THE FORKHEAD DOMAIN OF THE ADIPOCYTE-TRANSCRIPTION FACTOR FREAC-11 (S12)
Descriptor: S12 TRANSCRIPTION FACTOR (FKH-14)
Authors:van Dongen, M.J.P, Cederberg, A, Carlsson, P, Enerback, S, Wikstrom, M.
Deposit date:1999-10-12
Release date:2000-10-11
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure and dynamics of the DNA-binding domain of the adipocyte-transcription factor FREAC-11.
J.Mol.Biol., 296, 2000
1ZDT
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BU of 1zdt by Molmil
The Crystal Structure of Human Steroidogenic Factor-1
Descriptor: DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, Nuclear receptor coactivator 2, Steroidogenic factor 1
Authors:Wang, W, Zhang, C, Marimuthu, A, Krupka, H.I, Tabrizizad, M, Shelloe, R, Mehra, U, Eng, K, Nguyen, H, Settachatgul, C, Powell, B, Milburn, M.V, West, B.L.
Deposit date:2005-04-14
Release date:2005-05-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structures of human steroidogenic factor-1 and liver receptor homologue-1
Proc.Natl.Acad.Sci.USA, 102, 2005
5CXT
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BU of 5cxt by Molmil
Crystal structure of a RNA-binding protein 39 (RBM39) in complex with fragment of splicing factor (U2AF) from Unknown at 2.20 A resolution
Descriptor: RNA-binding protein 39, Splicing factor U2AF 65 kDa subunit
Authors:Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)
Deposit date:2015-07-29
Release date:2015-10-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:UHM-ULM interactions in the RBM39-U2AF65 splicing-factor complex.
Acta Crystallogr D Struct Biol, 72, 2016
5B4O
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BU of 5b4o by Molmil
Crystal structure of Macrophage Migration Inhibitory Factor in complex with BTZO-14
Descriptor: 1,2-ETHANEDIOL, 2-pyridin-3-yl-1,3-benzothiazin-4-one, Macrophage migration inhibitory factor, ...
Authors:Oki, H, Igaki, S, Moriya, Y, Hayano, Y, Habuka, N.
Deposit date:2016-04-07
Release date:2016-04-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:BTZO-1, a cardioprotective agent, reveals that macrophage migration inhibitory factor regulates ARE-mediated gene expression
Chem. Biol., 17, 2010
3ZD2
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BU of 3zd2 by Molmil
THE STRUCTURE OF THE TWO N-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 1 SHOWS FORMATION OF A NOVEL DIMERISATION INTERFACE
Descriptor: 1,2-ETHANEDIOL, COMPLEMENT FACTOR H-RELATED PROTEIN 1
Authors:Caesar, J.J.E, Goicoechea de Jorge, E, Pickering, M.C, Lea, S.M.
Deposit date:2012-11-23
Release date:2013-03-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Dimerization of Complement Factor H-Related Proteins Modulates Complement Activation in Vivo.
Proc.Natl.Acad.Sci.USA, 110, 2013
3ZD1
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BU of 3zd1 by Molmil
STRUCTURE OF THE TWO C-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 2
Descriptor: 1,2-ETHANEDIOL, COMPLEMENT FACTOR H-RELATED PROTEIN 2
Authors:Caesar, J.J.E, Goicoechea de Jorge, E, Pickering, M.C, Lea, S.M.
Deposit date:2012-11-23
Release date:2013-03-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Dimerization of Complement Factor H-Related Proteins Modulates Complement Activation in Vivo.
Proc.Natl.Acad.Sci.USA, 110, 2013
1F7M
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BU of 1f7m by Molmil
THE FIRST EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FVII, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: PROTEIN (Blood Coagulation Factor VII)
Authors:Kao, Y.-H, Lee, G.F, Wang, Y, Starovasnik, M.A, Kelley, R.F, Spellman, M.W, Lerner, L.
Deposit date:1999-02-19
Release date:1999-06-16
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII.
Biochemistry, 38, 1999
1F7E
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THE FIRST EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FVII, NMR, 20 STRUCTURES
Descriptor: PROTEIN (Blood Coagulation Factor VII)
Authors:Kao, Y.-H, Lee, G.F, Wang, Y, Starovasnik, M.A, Kelley, R.F, Spellman, M.W, Lerner, L.
Deposit date:1999-02-19
Release date:1999-06-16
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII.
Biochemistry, 38, 1999
1FF7
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BU of 1ff7 by Molmil
THE FIRST EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FVII (FUCOSYLATED AT SER-60), NMR, 20 STRUCTURES
Descriptor: PROTEIN (Blood Coagulation Factor VII), alpha-L-fucopyranose
Authors:Kao, Y.-H, Lee, G.F, Wang, Y, Starovasnik, M.A, Kelley, R.F, Spellman, M.W, Lerner, L.
Deposit date:1999-02-19
Release date:1999-06-16
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII.
Biochemistry, 38, 1999
1FFM
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BU of 1ffm by Molmil
THE FIRST EGF-LIKE DOMAIN FROM HUMAN BLOOD COAGULATION FVII (FUCOSYLATED AT SER-60), NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: PROTEIN (Blood Coagulation Factor VII), alpha-L-fucopyranose
Authors:Kao, Y.-H, Lee, G.F, Wang, Y, Starovasnik, M.A, Kelley, R.F, Spellman, M.W, Lerner, L.
Deposit date:1999-02-19
Release date:1999-06-16
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII.
Biochemistry, 38, 1999
1MFI
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BU of 1mfi by Molmil
CRYSTAL STRUCTURE OF MACROPHAGE MIGRATION INHIBITORY FACTOR COMPLEXED WITH (E)-2-FLUORO-P-HYDROXYCINNAMATE
Descriptor: 2-FLUORO-3-(4-HYDROXYPHENYL)-2E-PROPENEOATE, PROTEIN (MACROPHAGE MIGRATION INHIBITORY FACTOR)
Authors:Taylor, A.B, Johnson Jr, W.H, Czerwinski, R.M, Whitman, C.P, Hackert, M.L.
Deposit date:1998-08-12
Release date:1999-06-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of macrophage migration inhibitory factor complexed with (E)-2-fluoro-p-hydroxycinnamate at 1.8 A resolution: implications for enzymatic catalysis and inhibition.
Biochemistry, 38, 1999
5DQE
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BU of 5dqe by Molmil
Crystal structure of human transcription factor TEAD2 in complex with bromo-fenamic acid
Descriptor: 2-[(3-bromophenyl)amino]benzoic acid, Transcriptional enhancer factor TEF-4
Authors:Han, X, Luo, X.
Deposit date:2015-09-14
Release date:2015-11-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.183 Å)
Cite:Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic Strategy.
Structure, 23, 2015
5DQ8
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BU of 5dq8 by Molmil
Crystal structure of human transcription factor TEAD2 in complex with flufenamic acid
Descriptor: 2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID, Transcriptional enhancer factor TEF-4
Authors:Han, X, Luo, X.
Deposit date:2015-09-14
Release date:2015-11-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.305 Å)
Cite:Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic Strategy.
Structure, 23, 2015
3HMS
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BU of 3hms by Molmil
Crystal Crystal structure of the N-terminal fragment (28-126) of the human hepatocyte growth factor/scatter factor, orthorhombic crystal form
Descriptor: Hepatocyte growth factor, SULFATE ION
Authors:Tolbert, W.D.
Deposit date:2009-05-29
Release date:2010-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for agonism and antagonism of hepatocyte growth factor.
Proc.Natl.Acad.Sci.USA, 107, 2010
3HMT
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BU of 3hmt by Molmil
Crystal structure of the N-terminal fragment (28-126) of the human hepatocyte growth factor/scatter factor, trigonal crystal form
Descriptor: Hepatocyte growth factor
Authors:Tolbert, W.D.
Deposit date:2009-05-29
Release date:2010-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for agonism and antagonism of hepatocyte growth factor.
Proc.Natl.Acad.Sci.USA, 107, 2010
3HMR
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BU of 3hmr by Molmil
Crystal structure of the N-terminal fragment (31-127) of the mouse hepatocyte growth factor/scatter factor
Descriptor: Hepatocyte growth factor, SULFATE ION
Authors:Tolbert, W.D.
Deposit date:2009-05-29
Release date:2010-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for agonism and antagonism of hepatocyte growth factor.
Proc.Natl.Acad.Sci.USA, 107, 2010
3HN4
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BU of 3hn4 by Molmil
Crystal structure of the NK2 fragment (28-289) of human hepatocyte growth factor/scatter factor
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Hepatocyte growth factor, ...
Authors:Tolbert, W.D.
Deposit date:2009-05-29
Release date:2010-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for agonism and antagonism of hepatocyte growth factor.
Proc.Natl.Acad.Sci.USA, 107, 2010
1SI5
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BU of 1si5 by Molmil
Protease-like domain from 2-chain hepatocyte growth factor
Descriptor: hepatocyte growth factor
Authors:Kirchhofer, D, Yao, X, Peek, M, Eigenbrot, C, Lipari, M.T, Billeci, K.L, Maun, H.R, Moran, P, Santell, L, Lazarus, R.A.
Deposit date:2004-02-27
Release date:2004-12-28
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Structural and functional basis of the serine protease-like hepatocyte growth factor beta-chain in Met binding and signaling
J.Biol.Chem., 279, 2004
1JXS
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BU of 1jxs by Molmil
Solution Structure of the DNA-Binding Domain of Interleukin Enhancer Binding Factor
Descriptor: interleukin enhancer binding factor
Authors:Chuang, W.J, Liu, P.P, Li, C, Hsieh, Y.H, Chen, S.W, Chen, S.H, Jeng, W.Y.
Deposit date:2001-09-08
Release date:2003-03-11
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Solution structure of the DNA-binding domain of interleukin enhancer binding factor 1 (FOXK1a)
PROTEINS: STRUCT.,FUNCT.,GENET., 49, 2002
2LPN
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BU of 2lpn by Molmil
Solution Structure of N-Terminal domain of human Conserved Dopamine Neurotrophic Factor (CDNF)
Descriptor: Cerebral dopamine neurotrophic factor
Authors:Latge, C, Cabral, K.M.S, Foguel, D, Pires, J.R.M, Almeida, M.S.
Deposit date:2012-02-15
Release date:2013-02-20
Last modified:2013-05-22
Method:SOLUTION NMR
Cite:(1)H-, (13)C- and (15)N-NMR assignment of the N-terminal domain of human cerebral dopamine neurotrophic factor (CDNF).
Biomol.Nmr Assign., 7, 2013
2J76
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BU of 2j76 by Molmil
Solution structure and RNA interactions of the RNA recognition motif from eukaryotic translation initiation factor 4B
Descriptor: EUKARYOTIC TRANSLATION INITIATION FACTOR 4B
Authors:Fleming, K, Ghuman, J, Yuan, X.M, Simpson, P, Szendroi, A, Matthews, S, Curry, S.
Deposit date:2006-10-06
Release date:2008-10-28
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution Structure and RNA Interactions of the RNA Recognition Motif from Eukaryotic Translation Initiation Factor 4B.
Biochemistry, 42, 2003
8CN9
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BU of 8cn9 by Molmil
Factor VII binding Fab of the bispecific antibody HMB-001 in complex with Factor VII
Descriptor: CALCIUM ION, CESIUM ION, Coagulation factor VII, ...
Authors:Schluckebier, G, Johansson, E.
Deposit date:2023-02-22
Release date:2023-12-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:A bispecific antibody approach for the potential prophylactic treatment of inherited bleeding disorders
Nat Cardiovasc Res, 2023
1BDA
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BU of 1bda by Molmil
CATALYTIC DOMAIN OF HUMAN SINGLE CHAIN TISSUE PLASMINOGEN ACTIVATOR IN COMPLEX WITH DANSYL-EGR-CMK (DANSYL-GLU-GLY-ARG CHLOROMETHYL KETONE)
Descriptor: N-{[5-(dimethylamino)naphthalen-2-yl]sulfonyl}-L-alpha-glutamyl-N-[(1S)-4-{[amino(iminio)methyl]amino}-1-(chloroacetyl) butyl]glycinamide, SINGLE CHAIN TISSUE TYPE PLASMINOGEN ACTIVATOR
Authors:Bode, W, Renatus, M, Engh, R.A.
Deposit date:1998-05-07
Release date:1999-05-11
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Lysine 156 promotes the anomalous proenzyme activity of tPA: X-ray crystal structure of single-chain human tPA.
EMBO J., 16, 1997
4YT6
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BU of 4yt6 by Molmil
Factor VIIa in complex with the inhibitor 4-{[(R)-[5-ethoxy-2-fluoro-3-(propan-2-yloxy)phenyl](4-phenyl-1H-imidazol-2-yl)methyl]amino}benzenecarboximidamide
Descriptor: 4-[[(R)-(5-ethoxy-2-fluoranyl-3-propan-2-yloxy-phenyl)-(4-phenyl-1H-imidazol-2-yl)methyl]amino]benzenecarboximidamide, CALCIUM ION, Coagulation factor VII (heavy chain), ...
Authors:Wei, A.
Deposit date:2015-03-17
Release date:2015-04-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Design and synthesis of potent, selective phenylimidazole-based FVIIa inhibitors.
Bioorg.Med.Chem.Lett., 25, 2015

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