3HN4
Crystal structure of the NK2 fragment (28-289) of human hepatocyte growth factor/scatter factor
Summary for 3HN4
| Entry DOI | 10.2210/pdb3hn4/pdb |
| Related | 1BHT 1GMN 1GMO 1GP9 1NK1 2HGF 2QJ2 2QJ4 3HMR 3HMS 3HMT |
| Descriptor | Hepatocyte growth factor, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total) |
| Functional Keywords | hgf/sf, hormone/growth factor, disulfide bond, glycoprotein, growth factor, kringle, serine protease homolog, hormone |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 31358.51 |
| Authors | Tolbert, W.D. (deposition date: 2009-05-29, release date: 2010-06-09, Last modification date: 2023-09-06) |
| Primary citation | Tolbert, W.D.,Daugherty-Holtrop, J.,Gherardi, E.,Vande Woude, G.,Xu, H.E. Structural basis for agonism and antagonism of hepatocyte growth factor. Proc.Natl.Acad.Sci.USA, 107:13264-13269, 2010 Cited by PubMed: 20624990DOI: 10.1073/pnas.1005183107 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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