3HN4

Crystal structure of the NK2 fragment (28-289) of human hepatocyte growth factor/scatter factor

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE EPE A 1001

Chain	Residue
A	SER161
A	HOH3005
A	HOH3005
A	GLU183
A	GLY185
A	GLY186
A	TRP188
A	PHE190
A	ARG197
A	TYR198
A	VAL200

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MPD A 1002

Chain	Residue
A	LYS60
A	ARG73

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MPD A 1003

Chain	Residue
A	ILE231

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 2001

Chain	Residue
A	ARG93
A	HIS241
A	ARG242
A	ARG279

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 2002

Chain	Residue
A	THR83
A	GLY169
A	LYS170
A	ASP171
A	GLN173
A	HOH3054

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Functional Information from PROSITE/UniProt

site_id	PS00021
Number of Residues	14
Details	KRINGLE_1 Kringle domain signature. YCRNprgeeggpWC

Chain	Residue	Details
A	TYR176-CYS189
A	TYR259-CYS271

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	86
Details	Domain: {"description":"PAN","evidences":[{"source":"PROSITE-ProRule","id":"PRU00315","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	78
Details	Domain: {"description":"Kringle 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00121","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	77
Details	Domain: {"description":"Kringle 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00121","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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