3HN4
Crystal structure of the NK2 fragment (28-289) of human hepatocyte growth factor/scatter factor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Hepatocyte growth factor | polymer | 264 | 30691.7 | 1 | UniProt (P14210) Pfam (PF00024) Pfam (PF00051) In PDB | Homo sapiens (human) | Scatter factor, SF, Hepatopoeitin-A, Hepatocyte growth factor alpha chain, Hepatocyte growth factor beta chain |
| 2 | A | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
| 3 | A | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 2 | Chemie (MPD) | |||
| 4 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence modifications
A: 28 - 289 (UniProt: P14210)
| PDB | External Database | Details |
|---|---|---|
| Gly 26 | - | expression tag |
| Ser 27 | - | expression tag |
| Glu 132 | Lys 132 | engineered mutation |
| Glu 134 | Arg 134 | engineered mutation |
| Ala 214 | Cys 214 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30691.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 666.8 | |
| All* | Total formula weight | 31358.5 |
