5B4O
Crystal structure of Macrophage Migration Inhibitory Factor in complex with BTZO-14
Summary for 5B4O
Entry DOI | 10.2210/pdb5b4o/pdb |
Descriptor | Macrophage migration inhibitory factor, 2-pyridin-3-yl-1,3-benzothiazin-4-one, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | isomerase |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted : P14174 |
Total number of polymer chains | 3 |
Total formula weight | 38952.92 |
Authors | Oki, H.,Igaki, S.,Moriya, Y.,Hayano, Y.,Habuka, N. (deposition date: 2016-04-07, release date: 2016-04-20, Last modification date: 2023-11-08) |
Primary citation | Kimura, H.,Sato, Y.,Tajima, Y.,Suzuki, H.,Yukitake, H.,Imaeda, T.,Kajino, M.,Oki, H.,Takizawa, M.,Tanida, S. BTZO-1, a cardioprotective agent, reveals that macrophage migration inhibitory factor regulates ARE-mediated gene expression Chem. Biol., 17:1282-1294, 2010 Cited by PubMed: 21168764DOI: 10.1016/j.chembiol.2010.10.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.37 Å) |
Structure validation
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