1MFI

CRYSTAL STRUCTURE OF MACROPHAGE MIGRATION INHIBITORY FACTOR COMPLEXED WITH (E)-2-FLUORO-P-HYDROXYCINNAMATE

Summary for 1MFI

Entry DOI	10.2210/pdb1mfi/pdb
Descriptor	PROTEIN (MACROPHAGE MIGRATION INHIBITORY FACTOR), 2-FLUORO-3-(4-HYDROXYPHENYL)-2E-PROPENEOATE (3 entities in total)
Functional Keywords	cytokine, macrophage, inflammatory response, tautomerase, viral protein
Biological source	Mus musculus (house mouse)
Cellular location	Secreted : P34884
Total number of polymer chains	3
Total formula weight	37692.50
Authors	Taylor, A.B.,Johnson Jr., W.H.,Czerwinski, R.M.,Whitman, C.P.,Hackert, M.L. (deposition date: 1998-08-12, release date: 1999-06-22, Last modification date: 2024-04-03)
Primary citation	Taylor, A.B.,Johnson Jr., W.H.,Czerwinski, R.M.,Li, H.S.,Hackert, M.L.,Whitman, C.P. Crystal structure of macrophage migration inhibitory factor complexed with (E)-2-fluoro-p-hydroxycinnamate at 1.8 A resolution: implications for enzymatic catalysis and inhibition. Biochemistry, 38:7444-7452, 1999 Cited by PubMed: 10360941 DOI: 10.1021/bi9904048 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation