PDB: 209 件ウェブページステータス検索Chemie searchBIRD

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4B2S	Solution structure of CCP modules 11-12 of complement factor H 分子名称: COMPLEMENT FACTOR H 著者 Makou, E, Mertens, H.D, Maciejewski, M, Soares, D.C, Matis, I, Schmidt, C.Q, Herbert, A.P, Svergun, D.I, Barlow, P.N. 登録日 2012-07-17 公開日 2012-10-17 最終更新日 2013-05-08 実験手法 SOLUTION NMR 主引用文献 Solution Structure of Ccp Modules 10-12 Illuminates Functional Architecture of the Complement Regulator, Factor H. J.Mol.Biol., 424, 2012
4B2R	Solution structure of CCP modules 10-11 of complement factor H 分子名称: COMPLEMENT FACTOR H 著者 Makou, E, Mertens, H.D.T, Maciejewski, M, Soares, D.C, Matis, I, Schmidt, C.Q, Herbert, A.P, Svergun, D.I, Barlow, P.N. 登録日 2012-07-17 公開日 2012-10-10 最終更新日 2019-09-25 実験手法 SOLUTION NMR 主引用文献 Solution Structure of Ccp Modules 10-12 Illuminates Functional Architecture of the Complement Regulator, Factor H. J.Mol.Biol., 424, 2012
3J24	CryoEM reconstruction of complement decay-accelerating factor 分子名称: Complement decay-accelerating factor 著者 Yoder, J.D, Hafenstein, S.H. 登録日 2012-08-17 公開日 2012-09-26 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (9 Å) 主引用文献 The Crystal Structure of a Coxsackievirus B3-RD Variant and a Refined 9-Angstrom Cryo-Electron Microscopy Reconstruction of the Virus Complexed with Decay-Accelerating Factor (DAF) Provide a New Footprint of DAF on the Virus Surface. J.Virol., 86, 2012
4AQB	MBL-Ficolin Associated Protein-1, MAP-1 aka MAP44 分子名称: CALCIUM ION, MANNAN-BINDING LECTIN SERINE PROTEASE 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Skjoedt, M.O, Roversi, P, Hummelshoj, T, Palarasah, Y, Johnson, S, Lea, S.M, Garred, P. 登録日 2012-04-16 公開日 2012-08-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Crystal Structure and Functional Characterization of the Complement Regulator Mannose-Binding Lectin (Mbl)/Ficolin-Associated Protein-1 (Map-1). J.Biol.Chem., 287, 2012
3TVJ	Catalytic fragment of MASP-2 in complex with its specific inhibitor developed by directed evolution on SGCI scaffold 分子名称: Mannan-binding lectin serine protease 2 A chain, Mannan-binding lectin serine protease 2 B chain, Protease inhibitor SGPI-2, ... 著者 Heja, D, Harmat, V, Dobo, J, Szasz, R, Kekesi, K.A, Zavodszky, P, Gal, P, Pal, G. 登録日 2011-09-20 公開日 2012-04-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2. J.Biol.Chem., 287, 2012
4DJZ	Catalytic fragment of masp-1 in complex with its specific inhibitor developed by directed evolution on sgci scaffold 分子名称: Mannan-binding lectin serine protease 1 heavy chain, Mannan-binding lectin serine protease 1 light chain, Protease inhibitor SGPI-2 著者 Heja, D, Harmat, V, Fodor, K, Wilmanns, M, Dobo, J, Kekesi, K.A, Zavodszky, P, Gal, P, Pal, G. 登録日 2012-02-03 公開日 2012-04-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2. J.Biol.Chem., 287, 2012
2YBY	Structure of domains 6 and 7 of the mouse complement regulator Factor H 分子名称: 1,2-ETHANEDIOL, COMPLEMENT FACTOR H 著者 Everett, R.J, Caesar, J.J.E, Johnson, S.J, Tang, C.M, Lea, S.M. 登録日 2011-03-30 公開日 2012-04-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules. Plos Pathog., 8, 2012
4E0S	Crystal Structure of C5b-6 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement C5, ... 著者 Aleshin, A.E, Stec, B, DiScipio, R, Liddington, R.C. 登録日 2012-03-05 公開日 2012-04-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (4.21 Å) 主引用文献 Crystal structure of c5b-6 suggests structural basis for priming assembly of the membrane attack complex. J.Biol.Chem., 287, 2012
3RJ3	Complement components factor H CCP19-20 (S1191L mutant) and C3D in complex 分子名称: Complement C3d fragment, Complement Factor H-related protein 1, GLYCEROL 著者 Morgan, H.P, Hannan, J.P. 登録日 2011-04-15 公開日 2012-03-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural and functional characterization of the product of disease-related factor h gene conversion. Biochemistry, 51, 2012
4A5W	Crystal structure of C5b6 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COMPLEMENT C5, ... 著者 Hadders, M.A, Bubeck, D, Forneris, F, Pangburn, M, Llorca, O, Lea, S.M, Gros, P. 登録日 2011-10-28 公開日 2012-03-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5B6 and Sc5B9. Cell Rep., 1, 2012
3SW0	Structure of the C-terminal region (modules 18-20) of complement regulator Factor H 分子名称: Complement factor H, GLYCEROL, PHOSPHATE ION 著者 Morgan, H.P, Guariento, M, Schmidt, C.Q, Barlow, P.N, Hannan, J.P. 登録日 2011-07-13 公開日 2012-03-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Analysis of the C-Terminal Region (Modules 18-20) of Complement Regulator Factor H (FH). Plos One, 7, 2012
3T5O	Crystal Structure of human Complement Component C6 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, Complement component C6, ... 著者 Aleshin, A.E, Stec, B, Bankston, L.A, DiScipio, R.G, Liddington, R.C. 登録日 2011-07-27 公開日 2012-02-01 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.869 Å) 主引用文献 Structure of Complement C6 Suggests a Mechanism for Initiation and Unidirectional, Sequential Assembly of Membrane Attack Complex (MAC). J.Biol.Chem., 287, 2012
3R62	Structure of complement regulator Factor H mutant, T1184R. 分子名称: Complement factor H, GLYCEROL 著者 Morgan, H.P, Jiang, J, Herbert, A.P, Kavanagh, D, Uhran, D, Barlow, P.N, Hannan, J.P. 登録日 2011-03-21 公開日 2011-06-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Crystallographic determination of the disease-associated T1184R variant of the complement Factor H. Acta Crystallogr.,Sect.D, 67, 2011
2XRD	Structure of the N-terminal four domains of the complement regulator Rat Crry 分子名称: COMPLEMENT REGULATORY PROTEIN CRRY 著者 Leath, K.J, Roversi, P, Johnson, S, Morgan, B.P, Lea, S.M. 登録日 2010-09-14 公開日 2011-06-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structures of the Rat Complement Regulator Crry. Acta Crystallogr.,Sect.F, 67, 2011
2XRB	Structure of the N-terminal four domains of the complement regulator Rat Crry 分子名称: 1,2-ETHANEDIOL, COMPLEMENT REGULATORY PROTEIN CRRY, SULFATE ION 著者 Leath, K.J, Roversi, P, Johnson, S, Morgan, B.P, Lea, S.M. 登録日 2010-09-13 公開日 2011-06-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structures of the Rat Complement Regulator Crry. Acta Crystallogr.,Sect.F, 67, 2011
3OED	The structure of the complex between complement receptor CR2 and its ligand complement fragment C3d 分子名称: Complement C3, Complement receptor type 2 著者 Isenman, D.E, van den Elsen, J.M.H. 登録日 2010-08-12 公開日 2011-05-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.16 Å) 主引用文献 A crystal structure of the complex between human complement receptor 2 and its ligand C3d. Science, 332, 2011
3OXU	Complement components factor H CCP19-20 and C3d in complex 分子名称: Complement C3, GLYCEROL, HF protein 著者 Morgan, H.P, Schmidt, C.Q, Guariento, M, Gillespie, D, Herbert, A.P, Mertens, H, Blaum, B.S, Svergun, D, Johansson, C.M, Uhrin, D, Barlow, P.N, Hannan, J.P. 登録日 2010-09-22 公開日 2011-02-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for engagement by complement factor H of C3b on a self surface. Nat.Struct.Mol.Biol., 18, 2011
2XQW	Structure of Factor H domains 19-20 in complex with complement C3d 分子名称: COMPLEMENT C3, COMPLEMENT FACTOR H 著者 Kajander, T, Lehtinen, M.J, Hyvarinen, S, Bhattacharjee, A, Leung, E, Isenman, D.E, Meri, S, Jokiranta, T.S, Goldman, A. 登録日 2010-09-07 公開日 2011-02-02 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.306 Å) 主引用文献 Dual Interaction of Factor H with C3D and Glycosaminoglycans in Host-Nonhost Discrimination by Complement. Proc.Natl.Acad.Sci.USA, 108, 2011
2XWJ	Crystal Structure of Complement C3b in Complex with Factor B 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3 ALPHA CHAIN, COMPLEMENT C3 BETA CHAIN, ... 著者 Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P. 登録日 2010-11-04 公開日 2011-01-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation. Science, 330, 2010
2XWB	Crystal Structure of Complement C3b in complex with Factors B and D 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3B ALPHA' CHAIN, ... 著者 Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P. 登録日 2010-11-01 公開日 2011-01-12 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.49 Å) 主引用文献 Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation. Science, 330, 2010
3IYP	The Interaction of Decay-accelerating Factor with Echovirus 7 分子名称: Capsid protein, Complement decay-accelerating factor, LAURIC ACID, ... 著者 Plevka, P, Hafenstein, S, Zhang, Y, Harris, K.G, Cifuente, J.O, Bowman, V.D, Chipman, P.R, Lin, F, Medof, D.E, Bator, C.M, Rossmann, M.G. 登録日 2010-04-07 公開日 2010-11-24 最終更新日 2024-01-31 実験手法 ELECTRON MICROSCOPY (7.2 Å) 主引用文献 Interaction of decay-accelerating factor with echovirus 7. J.Virol., 84, 2010
3O8E	Structure of extracelllar portion of CD46 in complex with Adenovirus type 11 knob 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DITHIANE DIOL, Fiber 36.1 kDa protein, ... 著者 Persson, B.D, Schmitz, N.B, Casasnovas, J.M, Stehle, T. 登録日 2010-08-03 公開日 2010-10-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 Structure of the extracellular portion of CD46 provides insights into its interactions with complement proteins and pathogens. Plos Pathog., 6, 2010
3NFP	Crystal structure of the Fab fragment of therapeutic antibody daclizumab in complex with IL-2Ra (CD25) ectodomain 分子名称: Heavy chain of Fab fragment of daclizumab, Interleukin-2 receptor subunit alpha, Light chain of Fab fragment of daclizumab 著者 Yang, H, Wang, J, Du, J, Zhong, C, Guo, Y, Ding, J. 登録日 2010-06-10 公開日 2010-09-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Structural basis of immunosuppression by the therapeutic antibody daclizumab Cell Res., 20, 2010
3KZJ	Structure of complement Factor H variant R1203A 分子名称: Complement factor H, SULFATE ION 著者 Bhattacharjee, A, Lehtinen, M.J, Kajander, T, Goldman, A, Jokiranta, T.S. 登録日 2009-12-08 公開日 2010-05-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Both domain 19 and domain 20 of factor H are involved in binding to complement C3b and C3d Mol.Immunol., 47, 2010
3KXV	Structure of complement Factor H variant Q1139A 分子名称: Complement factor H, SULFATE ION 著者 Bhattacharjee, A, Lehtinen, M.J, Kajander, T, Goldman, A, Jokiranta, T.S. 登録日 2009-12-04 公開日 2010-05-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.004 Å) 主引用文献 Both domain 19 and domain 20 of factor H are involved in binding to complement C3b and C3d Mol.Immunol., 47, 2010

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