3R62

Structure of complement regulator Factor H mutant, T1184R.

Summary for 3R62

• Entry DOI: 10.2210/pdb3r62/pdb
• Related: 2BZM
• Descriptor: Complement factor H, GLYCEROL (3 entities in total)
• Functional Keywords: complement, immunity, repeating sushi domain, regulator of complement activation, c3d, immune system
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P08603
• Total number of polymer chains: 2
• Total formula weight: 29751.86

Authors

Morgan, H.P.,Jiang, J.,Herbert, A.P.,Kavanagh, D.,Uhran, D.,Barlow, P.N.,Hannan, J.P. (deposition date: 2011-03-21, release date: 2011-06-29, Last modification date: 2023-09-13)

• Primary citation: Morgan, H.P.,Jiang, J.,Herbert, A.P.,Kavanagh, D.,Uhran, D.,Barlow, P.N.,Hannan, J.P.; Crystallographic determination of the disease-associated T1184R variant of the complement Factor H.; Acta Crystallogr.,Sect.D, 67:593-600, 2011

Experimental method

X-RAY DIFFRACTION (1.52 Å)