2YBY

Structure of domains 6 and 7 of the mouse complement regulator Factor H

Summary for 2YBY

Entry DOI	10.2210/pdb2yby/pdb
Descriptor	COMPLEMENT FACTOR H, 1,2-ETHANEDIOL (3 entities in total)
Functional Keywords	immune system, complement regulation, innate immunity, infection
Biological source	MUS MUSCULUS (HOUSE MOUSE)
Cellular location	Secreted: P06909
Total number of polymer chains	1
Total formula weight	14447.17
Authors	Everett, R.J.,Caesar, J.J.E.,Johnson, S.J.,Tang, C.M.,Lea, S.M. (deposition date: 2011-03-30, release date: 2012-04-18, Last modification date: 2023-12-20)
Primary citation	Johnson, S.,Tan, L.,Van Der Veen, S.,Caesar, J.,Goicoechea De Jorge, E.,Harding, R.J.,Bai, X.,Exley, R.M.,Ward, P.N.,Ruivo, N.,Trivedi, K.,Cumber, E.,Jones, R.,Newham, L.,Staunton, D.,Ufret-Vincenty, R.,Borrow, R.,Pickering, M.C.,Lea, S.M.,Tang, C.M. Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules. Plos Pathog., 8:2981-, 2012 Cited by PubMed: 23133374 DOI: 10.1371/JOURNAL.PPAT.1002981 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.58 Å)

Structure validation