3RJ3

Complement components factor H CCP19-20 (S1191L mutant) and C3D in complex

Summary for 3RJ3

• Entry DOI: 10.2210/pdb3rj3/pdb
• Related: 3OXU
• Descriptor: Complement C3d fragment, Complement Factor H-related protein 1, GLYCEROL, ... (4 entities in total)
• Functional Keywords: c3d-alpha-alpha barrel, complement component, factor h, protein binding
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P01024 Q03591
• Total number of polymer chains: 6
• Total formula weight: 151101.31

Authors

Morgan, H.P.,Hannan, J.P. (deposition date: 2011-04-15, release date: 2012-03-14, Last modification date: 2023-09-13)

• Primary citation: Herbert, A.P.,Kavanagh, D.,Johansson, C.,Morgan, H.P.,Blaum, B.S.,Hannan, J.P.,Barlow, P.N.,Uhrin, D.; Structural and functional characterization of the product of disease-related factor h gene conversion.; Biochemistry, 51:1874-1884, 2012; PubMed: 22320225; DOI: 10.1021/bi201689j

Experimental method

X-RAY DIFFRACTION (2.35 Å)