3RJ3
Complement components factor H CCP19-20 (S1191L mutant) and C3D in complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Complement C3d fragment | polymer | 317 | 35444.4 | 3 | UniProt (P01024) Pfam (PF07678) In PDB | Homo sapiens (human) | C3D |
| 2 | D, E, F | Complement Factor H-related protein 1 | polymer | 129 | 14799.9 | 3 | UniProt (Q03591) Pfam (PF00084) UniProt (by SIFTS) (P08603) In PDB | Homo sapiens (human) | FHR-1, H factor-like protein 1, H-factor-like 1, H36 |
| 3 | A, B, C, E | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 4 | water | water | 18.0 | 372 | Chemie (HOH) |
Sequence modifications
A, B, C: 3 - 310 (UniProt: P01024)
D, E, F: 1107 - 1231 (UniProt: Q03591)
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | expression tag |
| Pro -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Glu 0 | - | expression tag |
| Phe 1 | - | expression tag |
| Arg 2 | - | expression tag |
| Ala 17 | Cys 1010 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Glu 1103 | - | expression tag |
| Ala 1104 | - | expression tag |
| Glu 1105 | - | expression tag |
| Phe 1106 | - | expression tag |
| Val 1197 | Ala 296 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 150732.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 368.4 | |
| All* | Total formula weight | 151101.3 |
