3RJ3

Complement components factor H CCP19-20 (S1191L mutant) and C3D in complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Complement C3d fragment	polymer	317	35444.4	3	UniProt (P01024) Pfam (PF07678)	Homo sapiens (human)	C3D
2	D, E, F (D, E, F)	Complement Factor H-related protein 1	polymer	129	14799.9	3	UniProt (Q03591) Pfam (PF00084) UniProt (by SIFTS) (P08603)	Homo sapiens (human)	FHR-1, H factor-like protein 1, H-factor-like 1, H36
3	G, H, I, J (A, B, C, E)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
4	K, L, M, N, O... (A, B, C, D, E...)	water	water		18.0	372	Chemie (HOH)

Sequence modifications

A, B, C: 3 - 310 (UniProt: P01024)

PDB	External Database	Details
Gly -6	-	expression tag
Pro -5	-	expression tag
Leu -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Pro -1	-	expression tag
Glu 0	-	expression tag
Phe 1	-	expression tag
Arg 2	-	expression tag
Ala 17	Cys 1010	conflict

D, E, F: 1107 - 1231 (UniProt: Q03591)

PDB	External Database	Details
Glu 1103	-	expression tag
Ala 1104	-	expression tag
Glu 1105	-	expression tag
Phe 1106	-	expression tag
Val 1197	Ala 296	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	150732.9
Non-Polymers*	Number of molecules	4
	Total formula weight	368.4
All*	Total formula weight	151101.3

*Water molecules are not included.