4AQB
MBL-Ficolin Associated Protein-1, MAP-1 aka MAP44
Summary for 4AQB
Entry DOI | 10.2210/pdb4aqb/pdb |
Descriptor | MANNAN-BINDING LECTIN SERINE PROTEASE 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | blood clotting, mannan-binding protein, complement, ficolins, lectin complement pathway, mannose- binding lectin, mbl/ficolin associated protein-1, mbl/ficolin associated serine proteases, map1, map44 |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Secreted: P48740 |
Total number of polymer chains | 1 |
Total formula weight | 43360.89 |
Authors | Skjoedt, M.O.,Roversi, P.,Hummelshoj, T.,Palarasah, Y.,Johnson, S.,Lea, S.M.,Garred, P. (deposition date: 2012-04-16, release date: 2012-08-08, Last modification date: 2023-12-20) |
Primary citation | Skjoedt, M.O.,Roversi, P.,Hummelshoj, T.,Palarasah, Y.,Rosbjerg, A.,Johnson, S.,Lea, S.M.,Garred, P. Crystal Structure and Functional Characterization of the Complement Regulator Mannose-Binding Lectin (Mbl)/Ficolin-Associated Protein-1 (Map-1). J.Biol.Chem., 287:32913-, 2012 Cited by PubMed: 22854970DOI: 10.1074/JBC.M112.386680 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.2 Å) |
Structure validation
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