2XQW
Structure of Factor H domains 19-20 in complex with complement C3d
Summary for 2XQW
Entry DOI | 10.2210/pdb2xqw/pdb |
Related | 1C3D 1FHC 1GHQ 1HAQ 1HCC 1HFH 1HFI 1KOV 1W2S 2A73 2A74 2G7I 2HR0 2JGW 2JGX 2UWN 2V8E 2W80 2W81 2WII 2WIN 2WY7 2WY8 2XWB 2XWJ |
Descriptor | COMPLEMENT C3, COMPLEMENT FACTOR H (3 entities in total) |
Functional Keywords | immune system, complement alternative pathway, atypical hemolytic uremic syndrome, ahus, cfh, fh, c3b |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 3 |
Total formula weight | 80781.56 |
Authors | Kajander, T.,Lehtinen, M.J.,Hyvarinen, S.,Bhattacharjee, A.,Leung, E.,Isenman, D.E.,Meri, S.,Jokiranta, T.S.,Goldman, A. (deposition date: 2010-09-07, release date: 2011-02-02, Last modification date: 2023-12-20) |
Primary citation | Kajander, T.,Lehtinen, M.J.,Hyvarinen, S.,Bhattacharjee, A.,Leung, E.,Isenman, D.E.,Meri, S.,Goldman, A.,Jokiranta, T.S. Dual Interaction of Factor H with C3D and Glycosaminoglycans in Host-Nonhost Discrimination by Complement. Proc.Natl.Acad.Sci.USA, 108:2897-, 2011 Cited by PubMed: 21285368DOI: 10.1073/PNAS.1017087108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.306 Å) |
Structure validation
Download full validation report