2XWB
Crystal Structure of Complement C3b in complex with Factors B and D
Summary for 2XWB
Entry DOI | 10.2210/pdb2xwb/pdb |
Related | 1BIO 1C3D 1DFP 1DIC 1DLE 1DST 1DSU 1FDP 1GHQ 1HFD 1Q0P 1RRK 1RS0 1RTK 1W2S 2A73 2A74 2HR0 2WII 2WIN 2WY7 2WY8 2XQW 2XW9 2XWA 2XWJ |
Descriptor | COMPLEMENT C3B BETA CHAIN, COMPLEMENT C3B ALPHA' CHAIN, COMPLEMENT FACTOR B, ... (10 entities in total) |
Functional Keywords | immune system, pro-convertase, hydrolase, serine protease, conformational changes, alternative pathway |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Secreted: P01024 P01024 P00751 P00746 |
Total number of polymer chains | 8 |
Total formula weight | 566820.38 |
Authors | Forneris, F.,Ricklin, D.,Wu, J.,Tzekou, A.,Wallace, R.S.,Lambris, J.D.,Gros, P. (deposition date: 2010-11-01, release date: 2011-01-12, Last modification date: 2023-12-20) |
Primary citation | Forneris, F.,Ricklin, D.,Wu, J.,Tzekou, A.,Wallace, R.S.,Lambris, J.D.,Gros, P. Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation. Science, 330:1816-, 2010 Cited by PubMed: 21205667DOI: 10.1126/SCIENCE.1195821 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.49 Å) |
Structure validation
Download full validation report