1RRK

Crystal Structure Analysis of the Bb segment of Factor B

Summary for 1RRK

• Entry DOI: 10.2210/pdb1rrk/pdb
• Related: 1RS0 1RTK
• Descriptor: Complement factor B, IODIDE ION, SODIUM ION, ... (5 entities in total)
• Functional Keywords: factor b, bb, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P00751
• Total number of polymer chains: 1
• Total formula weight: 56719.83

Authors

Ponnuraj, K.,Xu, Y.,Macon, K.,Moore, D.,Volanakis, J.E.,Narayana, S.V. (deposition date: 2003-12-08, release date: 2004-12-14, Last modification date: 2023-08-23)

• Primary citation: Ponnuraj, K.,Xu, Y.,Macon, K.,Moore, D.,Volanakis, J.E.,Narayana, S.V.; Structural analysis of engineered Bb fragment of complement factor B: insights into the activation mechanism of the alternative pathway C3-convertase.; Mol.Cell, 14:17-28, 2004; PubMed: 15068800; DOI: 10.1016/S1097-2765(04)00160-1

Experimental method

X-RAY DIFFRACTION (2 Å)