1RTK

Crystal Structure Analysis of the Bb segment of Factor B complexed with 4-guanidinobenzoic acid

Summary for 1RTK

Entry DOI	10.2210/pdb1rtk/pdb
Related	1RRK 1RS0
Descriptor	Complement factor B Bb fragment, IODIDE ION, SODIUM ION, ... (6 entities in total)
Functional Keywords	factor b, bb, factor bb-inhibitor complex, hormone-growth factor complex, hormone/growth factor
Biological source	Homo sapiens (Human)
Cellular location	Secreted: P00751
Total number of polymer chains	1
Total formula weight	56864.38
Authors	Ponnuraj, K.,Xu, Y.,Macon, K.,Moore, D.,Volanakis, J.E.,Narayana, S.V. (deposition date: 2003-12-10, release date: 2004-12-14, Last modification date: 2023-08-23)
Primary citation	Ponnuraj, K.,Xu, Y.,Macon, K.,Moore, D.,Volanakis, J.E.,Narayana, S.V. Structural analysis of engineered Bb fragment of complement factor B: insights into the activation mechanism of the alternative pathway C3-convertase. Mol.Cell, 14:17-28, 2004 Cited by PubMed: 15068800 DOI: 10.1016/S1097-2765(04)00160-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation