1RTK
Crystal Structure Analysis of the Bb segment of Factor B complexed with 4-guanidinobenzoic acid
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD A 740 |
| Chain | Residue |
| A | HIS531 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD A 741 |
| Chain | Residue |
| A | HIS466 |
| A | NA748 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA A 745 |
| Chain | Residue |
| A | LYS594 |
| A | ASN719 |
| A | GLN722 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NA A 746 |
| Chain | Residue |
| A | ARG580 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NA A 748 |
| Chain | Residue |
| A | TYR292 |
| A | HIS322 |
| A | LYS323 |
| A | LEU324 |
| A | IOD741 |
| A | ALA290 |
| A | THR291 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 749 |
| Chain | Residue |
| A | SER253 |
| A | SER255 |
| A | THR328 |
| A | HOH989 |
| A | HOH990 |
| A | HOH991 |
| A | HOH992 |
| site_id | AC7 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE GBS A 750 |
| Chain | Residue |
| A | HIS501 |
| A | THR669 |
| A | ARG671 |
| A | SER674 |
| A | SER693 |
| A | TRP694 |
| A | GLY695 |
| A | VAL697 |
| A | ASP698 |
| A | HOH879 |
| A | HOH945 |
| A | HOH1007 |
| A | HOH1016 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| A | LEU497-CYS502 |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. NTcrGDSGGPLI |
| Chain | Residue | Details |
| A | ASN668-ILE679 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"10637221","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15016353","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1Q0P","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17310251","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"6546754","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (Glc) (glycation) lysine","evidences":[{"source":"PubMed","id":"2006911","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17310251","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19503103","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19574954","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"6546754","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2WIN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | ASP551 | |
| A | HIS501 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | GLY675 | |
| A | SER674 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | SER674 | |
| A | GLY672 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | SER674 | |
| A | ASP551 | |
| A | HIS501 |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | GLY675 | |
| A | SER674 | |
| A | ASP551 | |
| A | HIS501 |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | SER674 | |
| A | ASP551 | |
| A | GLY672 | |
| A | HIS501 |
