1RTK
Crystal Structure Analysis of the Bb segment of Factor B complexed with 4-guanidinobenzoic acid
Summary for 1RTK
Entry DOI | 10.2210/pdb1rtk/pdb |
Related | 1RRK 1RS0 |
Descriptor | Complement factor B Bb fragment, IODIDE ION, SODIUM ION, ... (6 entities in total) |
Functional Keywords | factor b, bb, factor bb-inhibitor complex, hormone-growth factor complex, hormone/growth factor |
Biological source | Homo sapiens (Human) |
Cellular location | Secreted: P00751 |
Total number of polymer chains | 1 |
Total formula weight | 56864.38 |
Authors | Ponnuraj, K.,Xu, Y.,Macon, K.,Moore, D.,Volanakis, J.E.,Narayana, S.V. (deposition date: 2003-12-10, release date: 2004-12-14, Last modification date: 2023-08-23) |
Primary citation | Ponnuraj, K.,Xu, Y.,Macon, K.,Moore, D.,Volanakis, J.E.,Narayana, S.V. Structural analysis of engineered Bb fragment of complement factor B: insights into the activation mechanism of the alternative pathway C3-convertase. Mol.Cell, 14:17-28, 2004 Cited by PubMed: 15068800DOI: 10.1016/S1097-2765(04)00160-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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