2G7I
Structure of Human Complement Factor H Carboxyl Terminal Domains 19-20: a Basis for Atypical Hemolytic Uremic Syndrome
Summary for 2G7I
Entry DOI | 10.2210/pdb2g7i/pdb |
Descriptor | Complement factor H (2 entities in total) |
Functional Keywords | sushi (ccp/scr) domain, complement, regulator, factor h, beta-1h globulin, immune system, atypical hemolytic uremic syndrome, heparin binding |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P08603 |
Total number of polymer chains | 1 |
Total formula weight | 14297.31 |
Authors | Jaakola, V.-P.,Jokiranta, T.S.,Goldman, A. (deposition date: 2006-02-28, release date: 2006-05-23, Last modification date: 2011-07-13) |
Primary citation | Jokiranta, T.S.,Jaakola, V.-P.,Lehtinen, M.J.,Parepalo, M.,Meri, S.,Goldman, A. Structure of complement factor H carboxyl-terminus reveals molecular basis of atypical haemolytic uremic syndrome. Embo J., 25:1784-1794, 2006 Cited by PubMed: 16601698DOI: 10.1038/sj.emboj.7601052 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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