2XQW
Structure of Factor H domains 19-20 in complex with complement C3d
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | COMPLEMENT C3 | polymer | 294 | 32898.7 | 2 | UniProt (P01024) Pfam (PF07678) In PDB | HOMO SAPIENS (HUMAN) | C3 AND PZP-LIKE ALPHA-2-MACROGLOBULIN DOMAIN-CONTAINING PROTEIN 1 |
2 | C | COMPLEMENT FACTOR H | polymer | 133 | 14984.1 | 1 | UniProt (P08603) Pfam (PF00084) In PDB | HOMO SAPIENS (HUMAN) | H FACTOR 1 |
3 | water | water | 18.0 | 193 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 294 (UniProt: P01024)
C: 1103 - 1231 (UniProt: P08603)
PDB | External Database | Details |
---|---|---|
Met 1 | - | expression tag |
Leu 2 | - | expression tag |
Ala 17 | Cys 1010 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ala 1099 | - | expression tag |
Gly 1100 | - | expression tag |
Ile 1101 | - | expression tag |
Gln 1102 | - | expression tag |
Gly 1119 | Asp 1119 | engineered mutation |
Ala 1139 | Gln 1139 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 80781.6 | |
All* | Total formula weight | 80781.6 |