2XQW
Structure of Factor H domains 19-20 in complex with complement C3d
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | COMPLEMENT C3 | polymer | 294 | 32898.7 | 2 | UniProt (P01024) Pfam (PF07678) | HOMO SAPIENS (HUMAN) | C3 AND PZP-LIKE ALPHA-2-MACROGLOBULIN DOMAIN-CONTAINING PROTEIN 1 |
| 2 | C (C) | COMPLEMENT FACTOR H | polymer | 133 | 14984.1 | 1 | UniProt (P08603) Pfam (PF00084) | HOMO SAPIENS (HUMAN) | H FACTOR 1 |
| 3 | D, E, F (A, B, C) | water | water | 18.0 | 193 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 294 (UniProt: P01024)
C: 1103 - 1231 (UniProt: P08603)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | expression tag |
| Leu 2 | - | expression tag |
| Ala 17 | Cys 1010 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 1099 | - | expression tag |
| Gly 1100 | - | expression tag |
| Ile 1101 | - | expression tag |
| Gln 1102 | - | expression tag |
| Gly 1119 | Asp 1119 | engineered mutation |
| Ala 1139 | Gln 1139 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 80781.6 | |
| All* | Total formula weight | 80781.6 |
