3LRI
| Solution structure and backbone dynamics of long-[Arg(3)]insulin-like growth factor-I | Descriptor: | PROTEIN (INSULIN-LIKE GROWTH FACTOR I) | Authors: | Laajoki, L.G, Francis, G.L, Wallace, J.C, Carver, J.A, Keniry, M.A. | Deposit date: | 1999-04-13 | Release date: | 2000-05-23 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure and backbone dynamics of long-[Arg(3)]insulin-like growth factor-I J.Biol.Chem., 275, 2000
|
|
3MTH
| X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL | Descriptor: | 4-HYDROXY-BENZOIC ACID METHYL ESTER, CHLORIDE ION, METHYLPARABEN INSULIN, ... | Authors: | Whittingham, J.L, Dodson, E.J, Moody, P.C.E, Dodson, G.G. | Deposit date: | 1995-09-13 | Release date: | 1996-01-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol. Biochemistry, 34, 1995
|
|
3E7Y
| Structure of human insulin | Descriptor: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | Authors: | Timofeev, V.I, Baidus, A.N, Kislitsyn, Y.A, Kuranova, I.P. | Deposit date: | 2008-08-19 | Release date: | 2009-02-24 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of human insulin to be published
|
|
3E7Z
| Structure of human insulin | Descriptor: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | Authors: | Timofeev, V.I, Lyashenko, A.V, Kislitsyn, Y.A, Baidus, A.N, Kuranova, I.P. | Deposit date: | 2008-08-19 | Release date: | 2009-02-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure of human insulin To be published
|
|
3EXX
| |
3FHP
| A neutron crystallographic analysis of a porcine 2Zn insulin at 2.0 A resolution | Descriptor: | Insulin, ZINC ION | Authors: | Iwai, W, Kurihara, K, Yamada, T, Kobayashi, Y, Ohnishi, Y, Tanaka, I, Takahashi, H, Niimura, N. | Deposit date: | 2008-12-09 | Release date: | 2009-10-20 | Last modified: | 2023-11-01 | Method: | NEUTRON DIFFRACTION (2 Å) | Cite: | A neutron crystallographic analysis of T6 porcine insulin at 2.1 A resolution Acta Crystallogr.,Sect.D, 65, 2009
|
|
3FQ9
| Design of an insulin analog with enhanced receptor-binding selectivity. Rationale, structure, and therapeutic implications | Descriptor: | Insulin, ZINC ION | Authors: | Zhao, M, Wan, Z.L, Whittaker, L, Xu, B, Phillips, N, Katsoyannis, P, Whittaker, J, Weiss, M.A. | Deposit date: | 2009-01-07 | Release date: | 2009-08-04 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Design of an insulin analog with enhanced receptor binding selectivity: rationale, structure, and therapeutic implications. J.Biol.Chem., 284, 2009
|
|
3GF1
| |
3GKY
| The Structural Basis of an ER Stress-Associated Bottleneck in a Protein Folding Landscape | Descriptor: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | Authors: | Liu, M, Wan, Z.L, Chu, Y.C, Alddin, H, Klaproth, B, Weiss, M.A. | Deposit date: | 2009-03-11 | Release date: | 2009-03-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of a "nonfoldable" insulin: IMPAIRED FOLDING EFFICIENCY DESPITE NATIVE ACTIVITY. J.Biol.Chem., 284, 2009
|
|
3I40
| Human insulin | Descriptor: | Insulin A chain, Insulin B chain | Authors: | Timofeev, V.I, Bezuglov, V.V, Miroshnikov, K.A, Chuprov-Netochin, R.N, Kuranova, I.P. | Deposit date: | 2009-07-01 | Release date: | 2010-01-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | X-ray investigation of gene-engineered human insulin crystallized from a solution containing polysialic acid. Acta Crystallogr.,Sect.F, 66, 2010
|
|
3I3Z
| Human insulin | Descriptor: | Insulin A chain, Insulin B chain | Authors: | Timofeev, V.I, Bezuglov, V.V, Miroshnikov, K.A, Cuprov-Netochin, R.N, Samigina, V.R, Kuranova, I.P. | Deposit date: | 2009-07-01 | Release date: | 2010-01-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | X-ray investigation of gene-engineered human insulin crystallized from a solution containing polysialic acid. Acta Crystallogr.,Sect.F, 66, 2010
|
|
8PJC
| |
8PI4
| |
8PI6
| Crystal structure of the monomeric zinc free human insulin A22K, B3E, B26E, B29R, desB30 precursor with a Ser-Glu-Asp-Trp-Trp-Arg C-peptide and a Glu-Glu-Gly-Glu-Pro-Arg N-terminal extension | Descriptor: | Insulin B chain,Insulin A chain | Authors: | Johansson, E, Schluckebier, G. | Deposit date: | 2023-06-21 | Release date: | 2023-11-08 | Last modified: | 2024-04-17 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
|
|
8PJH
| |
8PI5
| |
8ONK
| |
8ONI
| Human insulin in complex with the analytical antibody S1 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of analytical antibody S1 Fab, Insulin A chain, ... | Authors: | Johansson, E. | Deposit date: | 2023-04-03 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Macromolecular structure of insulin and IgE clonality impacts IgE-mediated activation of sensitized basophils To Be Published
|
|
8SBD
| Cryo-EM structure of insulin amyloid-like fibril that is composed of two antiparallel protofilaments | Descriptor: | Insulin A chain, Insulin B chain | Authors: | Wang, L.W, Hall, C, Uchikawa, E, Chen, D.L, Choi, E, Zhang, X.W, Bai, X.C. | Deposit date: | 2023-04-03 | Release date: | 2023-08-30 | Last modified: | 2023-09-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis of insulin fibrillation. Sci Adv, 9, 2023
|
|
5L3N
| D11 bound [N29, S39_PQ]-IGF-II | Descriptor: | Insulin-like growth factor II | Authors: | Hexnerova, R. | Deposit date: | 2016-05-23 | Release date: | 2016-08-10 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
|
|
5L3L
| D11 bound IGF-II | Descriptor: | Insulin-like growth factor II | Authors: | Hexnerova, R. | Deposit date: | 2016-05-23 | Release date: | 2016-08-10 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
|
|
5L3M
| D11 bound [S39_PQ]-IGF-II | Descriptor: | Insulin-like growth factor II | Authors: | Hexnerova, R. | Deposit date: | 2016-05-23 | Release date: | 2016-08-10 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
|
|
5LIS
| |
5MIZ
| |
5MHD
| |