3E7Z

Structure of human insulin

Summary for 3E7Z

Related3E7Y
DescriptorInsulin A chain, Insulin B chain, ZINC ION, ... (5 entities in total)
Functional Keywordsinsulin, carbohydrate metabolism, cleavage on pair of basic residues, diabetes mellitus, disease mutation, glucose metabolism, hormone, pharmaceutical, secreted
Biological sourceHomo sapiens (Human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains4
Total molecular weight11634.82
Authors
Timofeev, V.I.,Lyashenko, A.V.,Kislitsyn, Y.A.,Baidus, A.N.,Kuranova, I.P. (deposition date: 2008-08-19, release date: 2009-02-24, Last modification date: 2011-07-13)
Primary citation
Timofeev, V.I.,Lyashenko, A.V.,Kislitsyn, Y.A.,Baidus, A.N.,Kuranova, I.P.
Structure of human insulin
To be published,
Experimental method
X-RAY DIFFRACTION (1.7 Å)
NMR Information
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2891003.4%16.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution