8PI5
Crystal structure of human insulin desB30 precursor with an Alanine-Methionine-Lysine C-peptide in hexamer (T3R3) conformation
Summary for 8PI5
Entry DOI | 10.2210/pdb8pi5/pdb |
Descriptor | Insulin B chain,Insulin A chain, ZINC ION, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | insulin, precursor, dimer, hormone |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 12467.17 |
Authors | Johansson, E.,Schluckebier, G. (deposition date: 2023-06-21, release date: 2023-11-08, Last modification date: 2024-04-17) |
Primary citation | Kjeldsen, T.,Andersen, A.S.,Hubalek, F.,Johansson, E.,Kreiner, F.F.,Schluckebier, G.,Kurtzhals, P. Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42:464-478, 2024 Cited by PubMed: 37880066DOI: 10.1016/j.tibtech.2023.09.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.66 Å) |
Structure validation
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