8PI5

Crystal structure of human insulin desB30 precursor with an Alanine-Methionine-Lysine C-peptide in hexamer (T3R3) conformation

Summary for 8PI5

Entry DOI	10.2210/pdb8pi5/pdb
Descriptor	Insulin B chain,Insulin A chain, ZINC ION, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	insulin, precursor, dimer, hormone
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	12467.17
Authors	Johansson, E.,Schluckebier, G. (deposition date: 2023-06-21, release date: 2023-11-08, Last modification date: 2024-04-17)
Primary citation	Kjeldsen, T.,Andersen, A.S.,Hubalek, F.,Johansson, E.,Kreiner, F.F.,Schluckebier, G.,Kurtzhals, P. Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42:464-478, 2024 Cited by PubMed: 37880066 DOI: 10.1016/j.tibtech.2023.09.012 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.66 Å)

Structure validation