8PI5

Crystal structure of human insulin desB30 precursor with an Alanine-Methionine-Lysine C-peptide in hexamer (T3R3) conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, D)	Insulin B chain,Insulin A chain	polymer	53	6030.0	2	UniProt (P01308) Pfam (PF00049)	Homo sapiens (human)
2	C, D, E, F (B, D)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
3	G (D)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4	H (D)	RESORCINOL	non-polymer		110.1	1	Chemie (RCO)
5	I, J (B, D)	water	water		18.0	94	Chemie (HOH)

Sequence modifications

B, D: 1 - 29 (UniProt: P01308)
B, D: 33 - 53 (UniProt: P01308)

PDB	External Database	Details
Ala 30	-	linker
Met 31	-	linker
Lys 32	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	12060.0
Non-Polymers*	Number of molecules	6
	Total formula weight	407.2
All*	Total formula weight	12467.2

*Water molecules are not included.