3EXX

Structure of the T6 human insulin derivative with nickel at 1.35 A resolution

Summary for 3EXX

DescriptorInsulin A chain, Insulin B chain, NICKEL (II) ION, ... (5 entities in total)
Functional Keywordsnickel insulin, carbohydrate metabolism, cleavage on pair of basic residues, diabetes mellitus, disease mutation, glucose metabolism, hormone, secreted
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains4
Total molecular weight11798.67
Authors
Prugovecki, B.,Matkovic-Calogovic, D. (deposition date: 2008-10-17, release date: 2009-05-19, Last modification date: 2011-09-07)
Primary citation
Prugovecki, B.,Dodson, E.,Dodson, G.,Matkovic-Calogovic, D.
Structure of the T6 Human Nickel Insulin Derivative at 1.35 A Resolution.
CROATICA CHEMICA ACTA, 82:433-438, 2009
Experimental method
X-RAY DIFFRACTION (1.35 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.1693401.1%4.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution