Structure of the T6 human insulin derivative with nickel at 1.35 A resolution

Summary for 3EXX

DescriptorInsulin A chain, Insulin B chain, NICKEL (II) ION, ... (5 entities in total)
Functional Keywordsnickel insulin, carbohydrate metabolism, cleavage on pair of basic residues, diabetes mellitus, disease mutation, glucose metabolism, hormone, secreted
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains4
Total molecular weight11798.67
Prugovecki, B.,Matkovic-Calogovic, D. (deposition date: 2008-10-17, release date: 2009-05-19, Last modification date: 2011-09-07)
Primary citation
Prugovecki, B.,Dodson, E.,Dodson, G.,Matkovic-Calogovic, D.
Structure of the T6 Human Nickel Insulin Derivative at 1.35 A Resolution.
CROATICA CHEMICA ACTA, 82:433-438, 2009
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.169340 1.1% 4.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-21