8PI4
Crystal structure of human insulin desB30 precursor with an Alanine-Methionine-Lysine C-peptide in dimer (T2) conformation
Summary for 8PI4
| Entry DOI | 10.2210/pdb8pi4/pdb |
| Descriptor | Insulin B chain,Insulin A chain (2 entities in total) |
| Functional Keywords | insulin, precursor, dimer, hormone |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 1 |
| Total formula weight | 6029.98 |
| Authors | Johansson, E.,Schluckebier, G. (deposition date: 2023-06-21, release date: 2023-11-08, Last modification date: 2024-04-17) |
| Primary citation | Kjeldsen, T.,Andersen, A.S.,Hubalek, F.,Johansson, E.,Kreiner, F.F.,Schluckebier, G.,Kurtzhals, P. Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42:464-478, 2024 Cited by PubMed: 37880066DOI: 10.1016/j.tibtech.2023.09.012 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
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