PDB: 435 件ウェブページステータス検索Chemie searchBIRD

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3LRI	Solution structure and backbone dynamics of long-[Arg(3)]insulin-like growth factor-I 分子名称: PROTEIN (INSULIN-LIKE GROWTH FACTOR I) 著者 Laajoki, L.G, Francis, G.L, Wallace, J.C, Carver, J.A, Keniry, M.A. 登録日 1999-04-13 公開日 2000-05-23 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Solution structure and backbone dynamics of long-[Arg(3)]insulin-like growth factor-I J.Biol.Chem., 275, 2000
3MTH	X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL 分子名称: 4-HYDROXY-BENZOIC ACID METHYL ESTER, CHLORIDE ION, METHYLPARABEN INSULIN, ... 著者 Whittingham, J.L, Dodson, E.J, Moody, P.C.E, Dodson, G.G. 登録日 1995-09-13 公開日 1996-01-29 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol. Biochemistry, 34, 1995
3E7Y	Structure of human insulin 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Timofeev, V.I, Baidus, A.N, Kislitsyn, Y.A, Kuranova, I.P. 登録日 2008-08-19 公開日 2009-02-24 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of human insulin to be published
3E7Z	Structure of human insulin 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Timofeev, V.I, Lyashenko, A.V, Kislitsyn, Y.A, Baidus, A.N, Kuranova, I.P. 登録日 2008-08-19 公開日 2009-02-24 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure of human insulin To be published
3EXX	Structure of the T6 human insulin derivative with nickel at 1.35 A resolution 分子名称: Insulin A chain, Insulin B chain, NICKEL (II) ION, ... 著者 Prugovecki, B, Matkovic-Calogovic, D. 登録日 2008-10-17 公開日 2009-05-19 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structure of the T6 Human Nickel Insulin Derivative at 1.35 A Resolution. CROATICA CHEMICA ACTA, 82, 2009
3FHP	A neutron crystallographic analysis of a porcine 2Zn insulin at 2.0 A resolution 分子名称: Insulin, ZINC ION 著者 Iwai, W, Kurihara, K, Yamada, T, Kobayashi, Y, Ohnishi, Y, Tanaka, I, Takahashi, H, Niimura, N. 登録日 2008-12-09 公開日 2009-10-20 最終更新日 2023-11-01 実験手法 NEUTRON DIFFRACTION (2 Å) 主引用文献 A neutron crystallographic analysis of T6 porcine insulin at 2.1 A resolution Acta Crystallogr.,Sect.D, 65, 2009
3FQ9	Design of an insulin analog with enhanced receptor-binding selectivity. Rationale, structure, and therapeutic implications 分子名称: Insulin, ZINC ION 著者 Zhao, M, Wan, Z.L, Whittaker, L, Xu, B, Phillips, N, Katsoyannis, P, Whittaker, J, Weiss, M.A. 登録日 2009-01-07 公開日 2009-08-04 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Design of an insulin analog with enhanced receptor binding selectivity: rationale, structure, and therapeutic implications. J.Biol.Chem., 284, 2009
3GF1	SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR 1: A NUCLEAR MAGNETIC RESONANCE AND RESTRAINED MOLECULAR DYNAMICS STUDY 分子名称: INSULIN-LIKE GROWTH FACTOR I 著者 Cooke, R.M, Harvey, T.S, Campbell, I.D. 登録日 1991-01-24 公開日 1993-04-15 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study. Biochemistry, 30, 1991
3GKY	The Structural Basis of an ER Stress-Associated Bottleneck in a Protein Folding Landscape 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Liu, M, Wan, Z.L, Chu, Y.C, Alddin, H, Klaproth, B, Weiss, M.A. 登録日 2009-03-11 公開日 2009-03-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of a "nonfoldable" insulin: IMPAIRED FOLDING EFFICIENCY DESPITE NATIVE ACTIVITY. J.Biol.Chem., 284, 2009
3I40	Human insulin 分子名称: Insulin A chain, Insulin B chain 著者 Timofeev, V.I, Bezuglov, V.V, Miroshnikov, K.A, Chuprov-Netochin, R.N, Kuranova, I.P. 登録日 2009-07-01 公開日 2010-01-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 X-ray investigation of gene-engineered human insulin crystallized from a solution containing polysialic acid. Acta Crystallogr.,Sect.F, 66, 2010
3I3Z	Human insulin 分子名称: Insulin A chain, Insulin B chain 著者 Timofeev, V.I, Bezuglov, V.V, Miroshnikov, K.A, Cuprov-Netochin, R.N, Samigina, V.R, Kuranova, I.P. 登録日 2009-07-01 公開日 2010-01-05 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 X-ray investigation of gene-engineered human insulin crystallized from a solution containing polysialic acid. Acta Crystallogr.,Sect.F, 66, 2010
8PJC	Crystal structure of human insulin desB30 precursor with an Alanine-Alanine-Lysine C-peptide in dimer (T2) conformation 分子名称: Insulin 著者 Schluckebier, G, Johansson, E. 登録日 2023-06-23 公開日 2023-11-08 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
8PI4	Crystal structure of human insulin desB30 precursor with an Alanine-Methionine-Lysine C-peptide in dimer (T2) conformation 分子名称: Insulin B chain,Insulin A chain 著者 Johansson, E, Schluckebier, G. 登録日 2023-06-21 公開日 2023-11-08 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
8PI6	Crystal structure of the monomeric zinc free human insulin A22K, B3E, B26E, B29R, desB30 precursor with a Ser-Glu-Asp-Trp-Trp-Arg C-peptide and a Glu-Glu-Gly-Glu-Pro-Arg N-terminal extension 分子名称: Insulin B chain,Insulin A chain 著者 Johansson, E, Schluckebier, G. 登録日 2023-06-21 公開日 2023-11-08 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
8PJH	Crystal structure of human insulin desB30 precursor with an Aspartate-Glycine-Lysine C-peptide in dimer (T2) conformation 分子名称: Insulin 著者 Schluckebier, G, Johansson, E. 登録日 2023-06-23 公開日 2023-11-08 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
8PI5	Crystal structure of human insulin desB30 precursor with an Alanine-Methionine-Lysine C-peptide in hexamer (T3R3) conformation 分子名称: CHLORIDE ION, Insulin B chain,Insulin A chain, RESORCINOL, ... 著者 Johansson, E, Schluckebier, G. 登録日 2023-06-21 公開日 2023-11-08 最終更新日 2024-04-17 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Molecular engineering of insulin for recombinant expression in yeast. Trends Biotechnol, 42, 2024
8ONK	Human insulin in complex with the analytical antibody S1 Fab and the analytical antibody HUI-001 Fab 分子名称: Heavy chain of analytical antibody HUI-001 Fab, Heavy chain of analytical antibody S1 Fab, Insulin A chain, ... 著者 Johansson, E. 登録日 2023-04-03 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (3.403 Å) 主引用文献 Macromolecular structure of insulin and IgE clonality impacts IgE-mediated activation of sensitized basophils To Be Published
8ONI	Human insulin in complex with the analytical antibody S1 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of analytical antibody S1 Fab, Insulin A chain, ... 著者 Johansson, E. 登録日 2023-04-03 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Macromolecular structure of insulin and IgE clonality impacts IgE-mediated activation of sensitized basophils To Be Published
8SBD	Cryo-EM structure of insulin amyloid-like fibril that is composed of two antiparallel protofilaments 分子名称: Insulin A chain, Insulin B chain 著者 Wang, L.W, Hall, C, Uchikawa, E, Chen, D.L, Choi, E, Zhang, X.W, Bai, X.C. 登録日 2023-04-03 公開日 2023-08-30 最終更新日 2023-09-27 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural basis of insulin fibrillation. Sci Adv, 9, 2023
5L3N	D11 bound [N29, S39_PQ]-IGF-II 分子名称: Insulin-like growth factor II 著者 Hexnerova, R. 登録日 2016-05-23 公開日 2016-08-10 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
5L3L	D11 bound IGF-II 分子名称: Insulin-like growth factor II 著者 Hexnerova, R. 登録日 2016-05-23 公開日 2016-08-10 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
5L3M	D11 bound [S39_PQ]-IGF-II 分子名称: Insulin-like growth factor II 著者 Hexnerova, R. 登録日 2016-05-23 公開日 2016-08-10 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain. J.Biol.Chem., 291, 2016
5LIS	Insulin solved by Native SAD from a dataset collected in one second 分子名称: Insulin 著者 Casanas, A, Finke, A, Wang, M. 登録日 2016-07-15 公開日 2016-08-03 最終更新日 2016-09-28 実験手法 X-RAY DIFFRACTION (2.293 Å) 主引用文献 EIGER detector: application in macromolecular crystallography. Acta Crystallogr D Struct Biol, 72, 2016
5MIZ	MD ensemble of bovine insulin 分子名称: Insulin 著者 Efimov, S.V, Zgadzay, Y.O, Klochkov, V.V. 登録日 2016-11-29 公開日 2017-01-25 最終更新日 2019-05-08 実験手法 SOLUTION NMR 主引用文献 MD ensemble of bovine insulin To Be Published
5MHD	Biosynthetic engineered A22S-B3K-B31R human insulin monomer structure in water/acetonitrile solutions. 分子名称: Insulin 著者 Bocian, W, Kozerski, L, Bednarek, E, Sitkowski, J. 登録日 2016-11-24 公開日 2017-08-09 最終更新日 2019-05-08 実験手法 SOLUTION NMR 主引用文献 Structure and pharmaceutical formulation development of a new long-acting recombinant human insulin analog studied by NMR and MS. J Pharm Biomed Anal, 135, 2017

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