PDB: 435 件ウェブページステータス検索Chemie searchBIRD

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2R36	Crystal structure of ni human ARG-insulin 分子名称: CHLORIDE ION, Insulin, NICKEL (II) ION, ... 著者 Sreekanth, R, Pattabhi, V, Rajan, S.S. 登録日 2007-08-29 公開日 2008-09-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Metal induced structural changes observed in hexameric insulin Int.J.Biol.Macromol., 44, 2009
2RN5	Humal Insulin Mutant B31Lys-B32Arg 分子名称: Insulin 著者 Bocian, W, Kozerski, L. 登録日 2007-12-06 公開日 2008-10-28 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 NMR structure of biosynthetic engineered human insulin monomer B31(Lys)-B32(Arg) in water/acetonitrile solution. Comparison with the solution structure of native human insulin monomer Biopolymers, 89, 2008
2TCI	X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL 分子名称: THIOCYANATE INSULIN, THIOCYANATE ION, ZINC ION 著者 Whittingham, J.L, Dodson, E.J, Moody, P.C.E, Dodson, G.G. 登録日 1995-09-13 公開日 1996-01-29 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol. Biochemistry, 34, 1995
2W44	Structure DeltaA1-A4 insulin 分子名称: CHLORIDE ION, INSULIN, RESORCINOL, ... 著者 Thorsoee, K.S, Schlein, M, Brandt, J, Schluckebier, G, Naver, H. 登録日 2008-11-21 公開日 2009-12-22 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Kinetic Evidence for the Sequential Association of Insulin Binding Sites 1 and 2 to the Insulin Receptor and the Influence of Receptor Isoform. Biochemistry, 49, 2010
2VJZ	Crystal structure form ultalente insulin microcrystals 分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... 著者 Wagner, A, Diez, J, Schulze-Briese, C, Schluckebier, G. 登録日 2007-12-14 公開日 2008-09-16 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure of Ultralente-A Microcrystalline Insulin Suspension. Proteins, 74, 2009
2WS1	Semi-synthetic analogue of human insulin NMeTyrB26-insulin in monomer form 分子名称: ACETATE ION, INSULIN A CHAIN, INSULIN B CHAIN 著者 Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. 登録日 2009-09-03 公開日 2010-02-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues. Proc.Natl.Acad.Sci.USA, 107, 2010
2WS6	Semi-synthetic analogue of human insulin NMeTyrB26-insulin in hexamer form 分子名称: CHLORIDE ION, GLYCEROL, INSULIN A CHAIN, ... 著者 Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. 登録日 2009-09-03 公開日 2010-02-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues. Proc.Natl.Acad.Sci.USA, 107, 2010
2WS0	Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 7.5 分子名称: INSULIN A CHAIN, INSULIN B CHAIN 著者 Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. 登録日 2009-09-03 公開日 2010-02-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues. Proc.Natl.Acad.Sci.USA, 107, 2010
2VK0	Crystal structure form ultalente insulin microcrystals 分子名称: 4-HYDROXY-BENZOIC ACID METHYL ESTER, INSULIN A CHAIN, INSULIN B CHAIN, ... 著者 Wagner, A, Diez, J, Schulze-Briese, C, Schluckebier, G. 登録日 2007-12-14 公開日 2008-09-16 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of Ultralente--A Microcrystalline Insulin Suspension. Proteins, 74, 2009
2WRX	Semi-synthetic analogue of human insulin NMeAlaB26-insulin at pH 3.0 分子名称: INSULIN A CHAIN, INSULIN B CHAIN, SODIUM ION 著者 Brzozowski, A.M, Jiracek, J, Zakova, L, Antolikova, E, Watson, C.J, Turkenburg, J.P, Dodson, G.G. 登録日 2009-09-02 公開日 2010-02-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Implications for the Active Form of Human Insulin Based on the Structural Convergence of Highly Active Hormone Analogues. Proc.Natl.Acad.Sci.USA, 107, 2010
1SJT	MINI-PROINSULIN, TWO CHAIN INSULIN ANALOG MUTANT: DES B30, HIS(B 10)ASP, PRO(B 28)ASP, NMR, 20 STRUCTURES 分子名称: PROINSULIN 著者 Hua, Q.X, Hu, S.Q, Jia, W.H, Chu, Y.C, Burke, G.T, Wang, S.H, Katsoyannis, P.G, Weiss, M.A. 登録日 1997-10-09 公開日 1998-03-18 最終更新日 2021-11-03 実験手法 SOLUTION NMR 主引用文献 Mini-proinsulin and mini-IGF-I: homologous protein sequences encoding non-homologous structures. J.Mol.Biol., 277, 1998
1QJ0	HUMAN INSULIN HEXAMERS WITH CHAIN B HIS MUTATED TO TYR 分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... 著者 Tang, L, Whittingham, J.L, Verma, C.S, Caves, L.S.D, Dodson, G.G. 登録日 1999-06-18 公開日 1999-06-22 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Consequences of the B5 Histidine --> Tyrosine Mutation in Human Insulin Characterized by X-Ray Crystallography and Conformational Analysis. Biochemistry, 38, 1999
3W80	Crystal structure of dodecamer human insulin with double C-axis length of the hexamer 2 Zn insulin cell 分子名称: Insulin, ZINC ION 著者 Murayoshi, M, Sasaki, K, Sakabe, N, Sakabe, K. 登録日 2013-03-11 公開日 2013-07-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure of dodecamer insulin with double C-axis length of the hexamer 2 Zn insulin celll To be Published
1RWE	Enhancing the activity of insulin at receptor edge: crystal structure and photo-cross-linking of A8 analogues 分子名称: CHLORIDE ION, Insulin, PHENOL, ... 著者 Wan, Z, Xu, B, Chu, Y.C, Li, B, Nakagawa, S.H, Qu, Y, Hu, S.Q, Katsoyannis, P.G, Weiss, M.A. 登録日 2003-12-16 公開日 2005-02-15 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Enhancing the activity of insulin at the receptor interface: crystal structure and photo-cross-linking of A8 analogues. Biochemistry, 43, 2004
1T1K	NMR STRUCTURE OF HUMAN INSULIN MUTANT HIS-B10-ASP, VAL-B12-ALA, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES 分子名称: Insulin 著者 Huang, K, Xu, B, Hu, S.Q, Chu, Y.C, Hua, Q.X, Whittaker, J, Nakagawa, S.H, De Meyts, P, Katsoyannis, P.G, Weiss, M.A. 登録日 2004-04-16 公開日 2004-08-10 最終更新日 2021-10-27 実験手法 SOLUTION NMR 主引用文献 How Insulin Binds: the B-Chain alpha-Helix Contacts the L1 beta-Helix of the Insulin Receptor. J.Mol.Biol., 341, 2004
1TYL	THE STRUCTURE OF A COMPLEX OF HEXAMERIC INSULIN AND 4'-HYDROXYACETANILIDE 分子名称: CHLORIDE ION, INSULIN, N-(4-HYDROXYPHENYL)ACETAMIDE (TYLENOL), ... 著者 Smith, G.D, Ciszak, E. 登録日 1994-06-21 公開日 1994-09-30 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The structure of a complex of hexameric insulin and 4'-hydroxyacetanilide. Proc.Natl.Acad.Sci.USA, 91, 1994
3V19	Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health 分子名称: CHLORIDE ION, Insulin, PHENOL, ... 著者 Wan, Z.L, Hua, Q.X, Wickramasinghe, N.P, Huang, K, Petkova, A.T, Hu, S.Q, Phillips, N.B, Yeh, I.J, Whittake, J, Ismail-Beigi, F, Katsoyyannis, P.G, Tycko, R, Weiss, M.A. 登録日 2011-12-09 公開日 2012-12-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health To be Published
3U4N	A novel covalently linked insulin dimer 分子名称: Insulin A chain, Insulin B chain 著者 Norrman, M, Vinther, T.N. 登録日 2011-10-10 公開日 2012-04-11 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Novel covalently linked insulin dimer engineered to investigate the function of insulin dimerization. Plos One, 7, 2012
1T1Q	NMR STRUCTURE OF HUMAN INSULIN MUTANT HIS-B10-ASP, VAL-B12-ABA, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES 分子名称: Insulin, insulin 著者 Huang, K, Xu, B, Hu, S.Q, Chu, Y.C, Hua, Q.X, Whittaker, J, Nakagawa, S.H, De Meyts, P, Katsoyannis, P.G, Weiss, M.A. 登録日 2004-04-16 公開日 2004-08-10 最終更新日 2021-10-27 実験手法 SOLUTION NMR 主引用文献 How Insulin Binds: the B-Chain alpha-Helix Contacts the L1 beta-Helix of the Insulin Receptor. J.Mol.Biol., 341, 2004
1T0C	Solution Structure of Human Proinsulin C-Peptide 分子名称: Insulin 著者 Munte, C.E, Vilela, L, Kalbitzer, H.-R, Garratt, R.C. 登録日 2004-04-08 公開日 2005-08-16 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 Solution structure of human proinsulin C-peptide Febs J., 272, 2005
3ZS2	TyrB25,NMePheB26,LysB28,ProB29-insulin analogue crystal structure 分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... 著者 Antolikova, E, Zakova, L, Turkenburg, J.P, Watson, C.J, Hanclova, I, Sanda, M, Cooper, A, Kraus, T, Brzozowski, A.M, Jiracek, J.A. 登録日 2011-06-21 公開日 2011-08-31 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Non-Equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface. J.Biol.Chem., 286, 2011
1TYM	THE STRUCTURE OF A COMPLEX OF HEXAMERIC INSULIN AND 4'-HYDROXYACETANILIDE 分子名称: CHLORIDE ION, INSULIN, N-(4-HYDROXYPHENYL)ACETAMIDE (TYLENOL), ... 著者 Smith, G.D, Ciszak, E. 登録日 1994-06-21 公開日 1994-09-30 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The structure of a complex of hexameric insulin and 4'-hydroxyacetanilide. Proc.Natl.Acad.Sci.USA, 91, 1994
3ZQR	NMePheB25 insulin analogue crystal structure 分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... 著者 Antolikova, E, Zakova, L, Turkenburg, J.P, Watson, C.J, Hanclova, I, Sanda, M, Cooper, A, Kraus, T, Brzozowski, A.M, Jiracek, J.A. 登録日 2011-06-10 公開日 2011-08-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Non-Equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface. J.Biol.Chem., 286, 2011
1QIY	HUMAN INSULIN HEXAMERS WITH CHAIN B HIS MUTATED TO TYR COMPLEXED WITH PHENOL 分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... 著者 Tang, L, Whittingham, J.L, Verma, C.S, Caves, L.S.D, Dodson, G.G. 登録日 1999-06-18 公開日 1999-06-22 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Consequences of the B5 Histidine --> Tyrosine Mutation in Human Insulin Characterized by X-Ray Crystallography and Conformational Analysis. Biochemistry, 38, 1999
3ZU1	Structure of LysB29(Nepsilon omega-carboxyheptadecanoyl) des(B30) Human Insulin 分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... 著者 Schluckebier, G, Whittingham, J. 登録日 2011-07-13 公開日 2011-08-03 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of Lysb29(Nepsilon Omega-Carboxyheptadecanoyl) Des(B30) Human Insulin To be Published

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