1RWE

Enhancing the activity of insulin at receptor edge: crystal structure and photo-cross-linking of A8 analogues

Summary for 1RWE

Related1MPJ
Descriptorinsulin, Insulin, ZINC ION, ... (6 entities in total)
Functional Keywordsa8-histidine human insulin, insulin receptor, hormone-growth factor complex, hormone/growth factor
Cellular locationSecreted P01308 P01308
Total number of polymer chains4
Total molecular weight12005.22
Authors
Wan, Z.,Xu, B.,Chu, Y.C.,Li, B.,Nakagawa, S.H.,Qu, Y.,Hu, S.Q.,Katsoyannis, P.G.,Weiss, M.A. (deposition date: 2003-12-16, release date: 2005-02-15, Last modification date: 2011-07-13)
Primary citation
Wan, Z.,Xu, B.,Huang, K.,Chu, Y.C.,Li, B.,Nakagawa, S.H.,Qu, Y.,Hu, S.Q.,Katsoyannis, P.G.,Weiss, M.A.
Enhancing the activity of insulin at the receptor interface: crystal structure and photo-cross-linking of A8 analogues.
Biochemistry, 43:16119-16133, 2004
PubMed: 15610006 (PDB entries with the same primary citation)
DOI: 10.1021/bi048223f
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8 Å)
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers1602.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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