1T1Q
NMR STRUCTURE OF HUMAN INSULIN MUTANT HIS-B10-ASP, VAL-B12-ABA, PRO-B28-LYS, LYS-B29-PRO, 15 STRUCTURES
Summary for 1T1Q
Entry DOI | 10.2210/pdb1t1q/pdb |
Related | 1LNP 1T1K 1T1P |
NMR Information | BMRB: 6205 |
Descriptor | insulin, Insulin (2 entities in total) |
Functional Keywords | aba-b12-dkp-insulin, protein unfolding, insulin receptor, receptor binding, hormone-growth factor complex, hormone/growth factor |
Cellular location | Secreted: P01308 P01308 |
Total number of polymer chains | 2 |
Total formula weight | 5780.57 |
Authors | Huang, K.,Xu, B.,Hu, S.Q.,Chu, Y.C.,Hua, Q.X.,Whittaker, J.,Nakagawa, S.H.,De Meyts, P.,Katsoyannis, P.G.,Weiss, M.A. (deposition date: 2004-04-16, release date: 2004-08-10, Last modification date: 2021-10-27) |
Primary citation | Huang, K.,Xu, B.,Hu, S.Q.,Chu, Y.C.,Hua, Q.X.,Qu, Y.,Li, B.,Wang, S.,Wang, R.Y.,Nakagawa, S.H.,Theede, A.M.,Whittaker, J.,De Meyts, P.,Katsoyannis, P.G.,Weiss, M.A. How Insulin Binds: the B-Chain alpha-Helix Contacts the L1 beta-Helix of the Insulin Receptor. J.Mol.Biol., 341:529-550, 2004 Cited by PubMed: 15276842DOI: 10.1016/j.jmb.2004.05.023 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report